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Have you written
Tip
Tip

Help us improve our Evidence Hub! Have you written a published paper about OpenMRS? Know of one that's not listed here? Add it!

This page is our online repository of the many studies conducted exploring OpenMRS. Collectively, these studies provide strong evidence for a variety of use cases: the impact of EMR use on care, secondary data use for site or regional or global program guidelines improvement, and the community open source model. The OpenMRS Community maintains the OpenMRS Evidence Base and adds new studies as they are discovered.

Over 3,860 publications are noted online involving OpenMRS - search query here.

Info
titleNote

This page is new and a work in progress as of August 2023. We are updating this with the thousands (warning) of articles published on OpenMRS with a bias towards recent articles from within the last few years.

...

Macatiag IV, J. J., Mariño, B. A. M., Pajes, A. N. N. I., & Yasay, E. B. (2024). Adenoma Detection Rate and Polyp Detection Rate among Gastroenterology Fellows and Consultants in a Tertiary Hospital in the Philippines: A Cross-sectional Study. Acta Medica Philippina.

...

Mental Health

Rural, Urban, Slum

Adult, Adolescent

...

Kallakuri, S., Gara, S., Godi, M., Yatirajula, S. K., Paslawar, S., Daniel, M., ... & Maulik, P. K. (2024). Learnings From Implementation of Technology-Enabled Mental Health Interventions in India: Implementation Report. JMIR Medical Informatics, 12, e47504.

...

Implementation

Infrastructure

HIV

...

Njuba, L., Gómez‐Morantes, J. E., Herrera, A., & Camacho, S. (2024). Health information systems in extreme contexts: Using mobile phones to fight AIDS in Uganda. The Electronic Journal of Information Systems in Developing Countries, e12314.

...

Excellent review of how OpenMRS has been used for HIV care in Uganda, and implementation details. 

Insightful Quote: "In the KHCIV ART clinic alone, (before) the OpenMRS (system) was introduced, there was a large room full of paper files of HIV patients missing from care, with only 23% of patients active in the program, meaning that the remaining 77% have been lost in care, died, or migrated."

...

Privacy

Regulation Compliance

Code Review

...

Expand
titleGuidelines on how to contribute to this page

  1. Decide if you want to contribute just a few times or regularly.

    1. If you just want to contribute right away: You can use this search query on Google Scholarto start finding publications that mention OpenMRS. You are welcome to use other academic search tools instead (such as PubMed); the reason we recommend Google Scholar is we find that this helps us discover mentions from LMIC-based authors whose work may not otherwise appear in academic search tools that favor journals from higher-income settings.

    2. If you want to regularly contribute: Sign up for Google Scholar alerts to your inbox at https://scholar.google.com/scholar_alerts 3. Use the search term “openmrs”. This ensures that you will get an email alert for any article that mentions “openmrs” or a similar term. Then when you receive automated email alerts, review the email. (Sometimes it is a false-alarm - e.g. sometimes you’ll get alerts for a totally unrelated system called “openMS”. You can ignore these.)

  2. Review the publication: If the alert looks like it really involves OpenMRS, open up the publication and see if it looks like it is from a legitimate source (such as a formal journal, reputable conference, or other trusted source like a Ministry of Health or implementing organization). Then, see if the article actually mentions anything of substance about OpenMRS. For example, if the article only mentions OpenMRS as a source in a footnote, this is not sufficient to be added to our Evidence page. The article should contribute some interesting knowledge to the OpenMRS community of implementers, developers, or researchers. Sometimes the article might be about some particular disease research, or open source processes, or eHealth leadership, or even cybersecurity practices.

  3. Add to the Wiki page following the table template.

    • The most important part here is the “Themes” so that people can quickly find articles of interest to them, or at least, proof that OpenMRS has had impact in multiple areas. (For example, in the past there was a myth that OpenMRS was only for HIV care (incorrect!), so it was important for us to show articles from other disease areas, such as Oncology, Endocrinology, and more.)

    • Use APA formatting (guidelines here, free generator here), as this is often the formatting standard that healthcare researchers expect, and thus communicates professionalism.

  4. Bonus: If you thought the article had an extra interesting quote or general finding, share that quote or note in the table for easy reference!

This page is our online repository of the many studies conducted exploring OpenMRS. Collectively, these studies provide strong evidence for a variety of use cases: the impact of EMR use on care, secondary data use for site or regional or global program guidelines improvement, and the community open source model. The OpenMRS Community maintains the OpenMRS Evidence Base and adds new studies as they are discovered.

Over 4,050 publications are noted online involving OpenMRS - search query here.

Info

Note

This page is new and a work in progress as of August 2023. We are gradually, iteratively updating this with the thousands (warning) of articles published on OpenMRS, strongly prioritizing recent articles from within the last few years.

Category

Citation

APA formatting preferred

Year

Country

Reference Key

URL

Misc. Notes

Implementation

Uwambajimana, E., Rugirangoga, P., Musabyimana, E., et al. (2024, August 25). Assessment of the use of electronic medical records system and barriers in Rwanda (Version 1) Preprint. Research Square. https://doi.org/10.

48550

21203/

arXiv

rs.

2401.07316Their study revealed that only 3.9% of the total OpenMRS codebase is made up of methods that are privacy-relevant and involved in personal data processing. This result highlights the precision of their approach in pinpointing privacy-relevant methods in applications.Open Source eHealthHaines, N. (2024). Sustainable Translation of Digital Health Technologies. Wellcome Open Res, 9(19), 19.2024GlobalHaines

3.rs-4763866/v1

2024

Rwanda

Uwambajimana 2024

https://

doi.org/10.21955/wellcomeopenres.1115374.1Helpful background on OpenMRS and comparison with other well known Open Source digital health solutions. 

Implementation

Infrastructure

HIV

Lober, W. B., Quiles, C., Wagner, S., Cassagnol, R., Lamothes, R., Alexis, D. R. P., Sutton, P., & Puttkammer, N. Three Years Experience with the Implementation of a Networked Electronic Medical Record in Haiti.2024HaitiLober 2024PDF

CyberSecurity

Payment Fraud Prevention

Saranya, A., Naresh, R., Karuppiah, S., & Jenifer, M. (2024). Development of trust-based authorization and authentication framework for secure electronic health payment in cloud environment. Soft Computing, 1-16.2024GlobalSaranya

www.researchsquare.com/article/rs-4763866/v1

Implementation

Interoperability

Architecture

Bakke, S. M. (2024). OpenMRS and Bahmni as an HIS in Ethiopia: Challenges with Integration and Interoperability with DHIS2 (Master's thesis). University of OSLO.

2024

Ethiopia

Bakke 2024

PDF

Process optimization

Implementation models

Avagyan, A., Minasyan, E., Khachatryan, H., Gevorgyan, S. (2024). Possible Process Optimization: Innovative Digital Health Implementation Models. In: Kozlakidis, Z., Muradyan, A., Sargsyan, K. (eds) Digitalization of Medicine in Low- and Middle-Income Countries. Sustainable Development Goals Series. Springer, Cham. https://doi.org/10.1007/978-3-031-62332-5_10

2024

Global

Avagyan 2024

https://link.springer.com/

article

chapter/10.1007/

s00500

978-3-

023

031-

09514-wHealth information exchange HIE; Data quality; Viral loadAniekwe, C., Cuffe, K., Audu, I., Nalda, N., Ibezim, B., Nnakwe, M., ... & Shrivastava, R. (2023). Assessing the effect of electronic health information exchange on the completeness and validity of data for measuring viral load testing turnaround time in Nigeria. International Journal of Medical Informatics, 174, 105059.2023NigeriaAniekwe 2023

62332-5_10

Diabetes

Hypertension

User Experience

Ntakirutimana, I., Kayiranga, D., Muhirwa, A., Nkurunziza, E., Sibomana, E., Uwamahoro, A., Igihozo, T., Ndoli, A., Niyonshuti, E., Rwubaka, E., Tuyishime, I., Umutoniwase, E. M., & Mugisha, M. (2024). Nurses' Experience of Using an Electronic Medical Records - OpenMRS Module for the Management of Hypertension and Diabetes in Rwanda: A Qualitative Study. Studies in health technology and informatics, 316, 1048–1052. https://doi.org/10.

1016/j.ijmedinf.2023.105059Demonstrated evidence of significant improvement in the quality of data available to measure viral load turnaround time with the implementation of HIE

COVID

HIV

Healthcare Workers

De Schacht C, Nhacule E, Belo C on behalf of the COVIV Study Collaborative Group, et al. Measuring the burden of SARS-CoV-2 infection among persons living with HIV and healthcare workers and its impact on service delivery in Mozambique: protocol of a prospective cohort studyBMJ Open 2023;13:e068988. 

2023MozambiqueDe Schacht 202310.1136/bmjopen-2022-068988 PHC Primary Health CareKumar, Rajesh. Application of digital technologies in primary healthcare: Opportunities & challenges. Indian Journal of Medical Research 157(4):p 276-279, April 2023. | DOI: 10.4103/ijmr.ijmr_3056_21 2023IndiaKumar 202310.4103/ijmr.ijmr_3056_21  

Machine Learning

Deduplication

Dixon, A., Thengo, L., Kitsao, E., Matiya, K., Barasa, M., Nyirongo, R., ... & Mbae, S. (2023). Community and Facility Health Information System Integration in Malawi: A Comparison of Machine Learning and Probabilistic Record Linkage Methods. ACM Journal on Computing and Sustainable Societies.2023MalawiDixon 2023https://doi.org/10.1145/3624773 

Accessibility

Visual Impairment

Human-Computer Interaction (HCI)

OpenMRS v2

Moncy, M. M., Pilli, M., Somasundaram, M., Purkayastha, S., & Fulton, C. R. (2023). Evaluation of accessibility of open-source EHRs for visually impaired users. arXiv preprint arXiv:2311.02531.2023GeneralMoncy 2023https://arxiv.org/abs/2311.02531#:~:text=https%3A//doi.org/10.48550/arXiv.2311.02531 

HIV ARV

Retention, Resistance

Joaquim, L., Miranda, M. N., Pimentel, V., Martins, M. D. R. O., Nhampossa, T., Abecasis, A., & Pingarilho, M. (2023). Retention in Care and Virological Failure among Adult HIV-Positive Patients on First-Line Antiretroviral Treatment in Maputo, Mozambique. Viruses, 15(10), 1978.2023MozambiqueJoaquim 2023https://doi.org/10.3390/v15101978 Anemia / AnaemiaAnton-Vazquez V, Mnzava D, Okuma J, Mlembe S, Lo Riso L, Sanchez JM, et al. (2023) Improving anaemia diagnosis using peripheral blood smear with remote interpretation in adults living with HIV with moderate to severe anaemia: A prospective study nested within the Kilombero and Ulanga antiretroviral cohort. PLoS ONE 18(10): e0293084. 2023TanzaniaAnton-Vazquez 2023https://doi.org/10.1371/journal.pone.0293084

EMR

IPV, GBV

HIV Index Case Testing (ICT)

Mbah, Rogers, Honoré, Ngend. A Review of Index Case Testing Induced Intimate Partner Violence and Electronic Management of Information in HIV Care. xx (2023). 2023CameroonMbah 202310.4236/etsn.2023.124005 Recommendations: • Data tools for HIV AIDS should integrate IPV indicators. • Include management of IPV survivors in existing EMR systems. • Develop more comprehensive EMRs that include complete care continua, especially for low-income settings. • Countries with limited resources should consider OPENMRS to implement EMR. • Screening for IPV among HIV patients should be scaled up to reduce IPV incidence. • IPV counseling services should be offered post-HIV test counseling to control IPV incidence rates.

Interoperability

Standards

Mehmood, N.Q., Mahfooz, S.Z., Faroom, S. et al. Usability evaluation of interoperability interfaces in electronic medical record systems. Health Serv Outcomes Res Method (2023). https://doi.org/10.1007/s10742-023-00312-32023GeneralMehmood 2023https://link.springer.com/article/10.1007/s10742-023-00312-3

Open Source

EMR

ICD 10

Capacity Building

Mougou, S. (2023). Building Stronger Healthcare in Tunisia: EHR Implementation with Open Software and Local Capacity Building. In Open Infrastructure Fund/Fondo de Infraestructura Abierta.2023TunisiaMougou, 2023https://openreview.net/forum?id=hVPDxT22ZeTesting three EHR systems to determine their suitability for meeting the requirements discussed by working groups. Assessing the capability to: integrate both clinical data and genomic data; the capacity to incorporate standardized medical vocabulary in both English and French languages; along with its alignment with ICD10 standardsOpen SourceKrasodomski-jones, A., & Eaves, D. (2023). Laying the Foundation for the Future: Open Source Sustainability and the Adoption of Digital Public Goods.2023GeneralKrasodomski-jones, 2023

https://policycommons.net/artifacts/3793098/laying-the-foundation-for-the-future/4598925/

Prenatal, ANC
EMRPrieto-Egido, I., Garrido Madrigal, A., & Barrena García, C. (2023, February). Development and Validation of a Health Information System to Improve Prenatal Controls in Guatemala. In International Congress on Information and Communication Technology (pp. 109-127). Singapore: Springer Nature Singapore.2023GuatemalaPrieto-Egido 2023

https://link.springer.com/chapter/10.1007/978-981-99-3091-3_10

CDS
HIVMagrabi, F., Cresswell, K., & Fraser, H. S. (2023). International dimensions of clinical decision support systems. In Clinical Decision Support and Beyond (pp. 145-188). Content Repository Only!.2023Kenya, RwandaMagrabi 2023

https://www.sciencedirect.com/science/article/abs/pii/B9780323912006000139

HIVMnzava, D., Okuma, J., Ndege, R., Kimera, N., Ntamatungiro, A., Nyuri, A., ... & Weisser, M. (2023). Decentralization of viral load testing to improve HIV care and treatment cascade in rural Tanzania: observational study from the Kilombero and Ulanga Antiretroviral Cohort. BMC Infectious Diseases, 23(1), 222.2023TanzaniaMnzava 2023https://link.springer.com/article/10.1186/s12879-023-08155-6

Open Source
Software Architecture, Architectural Smells, Software Performance

Arcelli Fontana, F., Camilli, M., Rendina, D., Taraboi, A. G., & Trubiani, C. (2023, June). Impact of Architectural Smells on Software Performance: an Exploratory Study. In Proceedings of the 27th International Conference on Evaluation and Assessment in Software Engineering (pp. 22-31).2023General
Team from: ItalyFontana 2023

https://dl.acm.org/doi/pdf/10.1145/3593434.3593442

Thyroid Cancer
Ultrasound
OncologyBisquera, Valparaiso, Perez, Uy, Espiritu, Pialago, Clarit. A Single Institution Experience on the Correlation of Kwak Thyroid Imaging Reporting and Data System Score (Kwak TIRADS) and Malignancy of Thyroid Nodules seen in a Tertiary Hospital Setting. World Cancer Research Journal, 10, e2498.2023PhilippinesBisquera 2023

https://www.wcrj.net/article/2498

Medical Training

Capacity Building

Stephanie Medlock, Kim J. Ploegmakers, Ronald Cornet, Kim Win Pang, Use of an open-source electronic health record to establish a “virtual hospital”: A tale of two curricula, International Journal of Medical Informatics, Volume 169, 2023, 104907, ISSN 1386-5056, https://doi.org/10.1016/j.ijmedinf.2022.104907.2023NetherlandsMedlock 2023https://www.sciencedirect.com/science/article/pii/S1386505622002210

COVID
Home monitoring

Sikder, A., Dickhoner, J., Kysh, L., Musheghyan, L., Shekherdimian, S., Levine, B., & Espinoza, J. (2022). International Collaboration to Develop a Remote Monitoring Web App for COVID-19 Patients in Armenia: Design and Development With Agile Methodology. JMIR Human Factors, 9(4), e40110.2022ArmeniaSikder 2022https://europepmc.org/article/med/36350739

The software was designed and developed over 2 months using human-centered design and agile sprints. Once live, 5087 patient records were created for 439 unique patients.

HIV
ART
Disease Survillance

Fataha, N. V. F. A., Gaveta, S., Langa, J. C., Banze, A. R., Sacarlal, J., Rossetto, E. V., ... & Kellogg, T. A. (2022). Evaluation of the Mozambique Antiretroviral Therapy (MozART) database as an antiretroviral therapy patient surveillance system, 2017-2018. The Pan African Medical Journal, 42.2022MozambiqueFataha 2022https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9429983/COVIDMirza, Muzna, Yoran Grant-Greene, Marie PJS Valles, Patrice Joseph, Stanley Juin, Stephan Brice, Patrick Dely et al. "Leveraging PEPFAR-supported health information systems for COVID-19 pandemic response." Emerging Infectious Diseases 28, no. Suppl 1 (2022): S49.2022HaitiMirza 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745247/

TuberculosisSiamisang, K., Rankgoane-Pono, G., Madisa, T. M., Mudiayi, T., & Tlhakanelo, J. T. (2022). Outcomes and predictors of tuberculosis mortality in Kweneng West District, Botswana: a retrospective cohort study. The Pan African Medical Journal, 42.2022BotswanaSiamisang 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142783/

OMOPEspinoza, J., Sikder, A., Lulejian, A., & Levine, B. (2022). Development of an OpenMRS-OMOP ETL tool to support informatics research and collaboration in LMICS. Available at SSRN 4075625.2022GeneralEspinoza 2022

https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4075625

Public Health
Open SourceWanger, J., Cullen, T., Dunbar, E. L., & Flowers, J. L. (2023). Open-source software for public health: opportunities and approaches. Sexually Transmitted Diseases, 50(8), S31.2022GeneralWanger 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348654/

HIV
ARTKisaka, A. M. (2022). Test and treat policy: Effect on ART initiation and retention and health system barriers and facilitators to implementation in AHF Uganda Cares Clinics in Central Uganda (Doctoral dissertation, Makerere University).2022UgandaKisaka 2022http://dspace.mak.ac.ug/handle/10570/10866

Results: The 30-days initiation rate was 62.7% before and 90.8% after the T&T policy rollout.

CDSFraser, H. S., Mugisha, M., Remera, E., Ngenzi, J. L., Richards, J., Santas, X., ... & Umubyeyi, A. (2022). User perceptions and use of an enhanced electronic health record in Rwanda with and without clinical alerts: cross-sectional survey. JMIR Medical Informatics, 10(5), e32305.2022RwandaFraser 2022https://medinform.jmir.org/2022/5/e32305/

A survey of user experience of a well established HIV implementation by the Rwanda MOH. Part of a larger OpenMRS research study of 112 health facilities in Rwanda.
The EHR top uses were to access client data easily or quickly (62/90, 69%), update patient records (56/89, 63%), create new patient records (49/88, 56%), generate various reports (38/85, 45%), and review previous records (43/89, 48%). In addition, >90% (81/90) of respondents agreed that the EHR made it easier to make informed decisions, was worth using, and has improved patient information quality. .... In intervention sites, staff were significantly more likely to update existing records (P=.04), generate summaries before (P<.001) or during visits (P=.01)

Maternity
Labor, DeliveryDinh, N., Agarwal, S., Avery, L., Ponnappan, P., Chelangat, J., Amendola, P., ... & Bartlett, L. (2022). Implementation Outcomes Assessment of a Digital Clinical Support Tool for Intrapartum Care in Rural Kenya: Observational Analysis. JMIR Formative Research, 6(6), e34741.2022KenyaDinh 2022

https://formative.jmir.org/2022/6/e34741

An example of the use of the VecnaCARES maternal child health package using OpenMRS and their custom hardware package for sites with no infrastructure.HIV
AdolescentAhimbisibwe, J. (2022). Factors associated with adherence to Anti-Retroviral Therapy (ART) among adolescents attending HIV clinic at China-Uganda Friendship Hospital-Naguru, Uganda (Doctoral dissertation, Makerere University).2022UgandaAhimbisibwe 2022

http://dspace.mak.ac.ug/handle/10570/10513

NTD

Ochoa, Rodrigo, Álvarez, Alessa, Freitas, Jordan, Purkayastha, Saptarshi, & Vélez, Iván D.. (2022). NTD Health: An electronic medical record system for neglected tropical diseases. Biomédica, 42(4), 602-610. Epub December 01, 2022.https://doi.org/10.7705/biomedica.62692022ColombiaOchoa 2022http://www.scielo.org.co/scielo.php?pid=S0120-41572022000400602&script=sci_arttext&tlng=enOpen SourcePaton C, Braa J, Muhire A, Marco-Ruiz L, Kobayashi S, Fraser H, Falcón L, Marcelo A. Open Source Digital Health Software for Resilient, Accessible and Equitable Healthcare Systems. Yearb Med Inform. 2022 Aug;31(1):67-73. doi: 10.1055/s-0042-1742508. Epub 2022 Jun 2. PMID: 35654431; PMCID: PMC9719763.2022GlobalPaton 2022https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719763Maternity
PMTCT
HEI
Mentor MothersCarlucci, J. G., Yu Z., Gonzalez P., Bravo M., Amorim G., das Felicidades Cugara, C., Guambe, H., Mucanhenga, J., Silva, W., Tique, J. A., Alvim, M. F. S., Graves, E., De Schact, C., Wester, W. The Effect of a Mentor Mothers Program on Maternal and Infant PMTCT Outcomes in Zambézia Province, Mozambique.2021MozambiqueCarlucci 2023

https://www.vumc.org/friends-in-global-health/sites/default/files/public_files/docs/11.%20VUMC-FGH_MM_Final%20Report%20ESoP%20Final%20Report_revised_18Nov2021_clean.pdf

EMR
Global Goods
Open SourceVerma N, Mamlin B, Flowers J, Acharya S, Labrique A, Cullen T. OpenMRS as a global good: Impact, opportunities, challenges, and lessons learned from fifteen years of implementation. Int J Med Inform. 2021 May;149:104405. doi: 10.1016/j.ijmedinf.2021.104405. Epub 2021 Feb 5. PMID: 33639327.2021GlobalVerma 2021

https://pubmed.ncbi.nlm.nih.gov/33639327/

Implementation
EMR
EmergencyMamlin, Burke W., Jennifer E. Shivers, Nancy K. Glober, and Jonathan J. Dick. "OpenMRS as an emergency EMR—How we used a global good to create an emergency EMR in a week." International Journal of Medical Informatics 149 (2021): 104433.2021USAMamlin 2021

https://www.sciencedirect.com/science/article/pii/S1386505621000599

ICD 11
APIMugisha, M., Byiringiro, J. B., Uwase, M., Abizeyimana, T., Ndikubwimana, B., Karema, N., ... & Tumusiime, D. (2020). Integration of International Classification of Diseases version 11 application program interface (API) in the Rwandan electronic medical records (openMRS): findings from two district hospitals in Rwanda. In The Importance of Health Informatics in Public Health during a Pandemic (pp. 280-283). IOS Press.2020RwandaMugisha 2020

https://ebooks.iospress.nl/doi/10.3233/SHTI200549

Michael Mugisha and colleague carry out research and implementation work with OpenMRS in Rwanda.

Machine Learning
HIV

Comparison of machine learning methods for predicting viral failure: a case study using electronic health record data.
Kimaina A, Dick J, DeLong A, Chrysanthopoulou SA, Kantor R, Hogan JW.Stat Commun Infect Dis. 2020 Nov 12;12(Suppl1):20190017.
2020Kimaina 2020

Translation of AMRS-based research for improving patient care.

This study was one of the precursors for a large research study on the use of machine learning to improve loss to follow up of HIV patients in Kenya 

Oncology
ChemotherapyKabukye, J. K., Casaceli, A. M., Ball, E., De Armas, M., & Cornet, R. (2019). Towards an open-source oncology electronic medical records system for low-resource settings: development of chemotherapy management in OpenMRS. In MEDINFO 2019: Health and Wellbeing e-Networks for All (pp. 634-638). IOS Press.2019Uganda
Malawi
Rwanda
Haiti
USAKabukye 2019

https://ebooks.iospress.nl/doi/10.3233/SHTI190300

Interoperability

Patient Transfer

Rweikiza, G., & Machuve, D. (2019). Development of medical records exchange system-a case of OpenMRS and Care2X. International Journal of Advanced Technology and Engineering Exploration, 6(52), 77-83.2019TanzaniaRweikiza 2019

https://www.accentsjournals.org/paperInfo.php?journalPaperId=1123

PDF

DiabetesYandrapalli, B. T., Jones, J., & Purkayastha, S. (2019). Development and Implementation of a Dashboard for Diabetes Care Management in OpenMRS. arXiv preprint arXiv:1910.11437.2019General

Yandrapalli 2019

https://arxiv.org/abs/1910.11437

https://arxiv.org/pdf/1910.11437.pdf

HIVHumphrey JM, Genberg BL, Keter A, Musick B, Apondi E, Gardner A, Hogan JW, Wools-Kaloustian K. Viral suppression among children and their caregivers living with HIV in western Kenya. J Int AIDS Soc. 2019 Apr;22(4):e25272. doi: 10.1002/jia2.25272. PubMed PMID: 30983148; PubMed Central PMCID: PMC6462809.2019KenyaHumphrey 2018

Helped understand the link between parental viral suppression and child suppression

Radiology, RISGichoya, J. W., Kohli, M., Ivange, L., Schmidt, T. S., & Purkayastha, S. (2018). A platform for innovation and standards evaluation: a case study from the OpenMRS open-source radiology information system. Journal of digital imaging, 31, 361-370.2018GeneralGichoya 2018

https://link.springer.com/article/10.1007/s10278-018-0088-5

HIV
MCH
LTFUHolmes CB, Yiannoutsos CT, Elul B, Bukusi E, Ssali J, Kambugu A, Musick BS, Cohen C, Williams C, Diero L, Padian N, Wools-Kaloustian KK. Increased prevalence of pregnancy and comparative risk of program attrition among individuals starting HIV treatment in East Africa. PLoS One. 2018 Jan 17;13(1):e0190828. doi: 10.1371/journal.pone.0190828. eCollection 2018. PubMed PMID: 29342180.2018Holmes 2018

Helped understand the impact of pregnancy and sex on retention in care

HIV
Drug Resistance
Pediatric

Wools-Kaloustian K, Marete I, Ayaya S, Sohn AH, Van Nguyen L, Li S, Leroy V, Musick BS, Newman JE, Edmonds A, Davies MA, Eboua FT, Obama MT, Yotebieng M, Sawry S, Mofenson LM, Yiannoutsos CT. Time to First-Line ART Failure and Time to Second-Line ART Switch in the IeDEA Pediatric Cohort. Journal of acquired immune deficiency syndromes. 2018; PubMed [journal] PMID: 295095902018

Wools-Kaloustian 2018

Helped identify delays in switching failed regimens.

EMR
Open SourceSyzdykova A, Malta A, Zolfo M, Diro E, Oliveira JL. Open-Source Electronic Health Record Systems for Low-Resource Settings: Systematic Review. JMIR Med Inform. 2017 Nov 13;5(4):e44. doi: 10.2196/medinform.8131. PMID: 29133283; PMCID: PMC5703976.2017GeneralSyzdykova 2017

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703976/

ANC, MCHE. Kimei and K. Kalegele, "Digitization of antenatal health card and integration with OpenMRS platform: System analysis and design," 2017 IST-Africa Week Conference (IST-Africa), Windhoek, Namibia, 2017, pp. 1-7, doi: 10.23919/ISTAFRICA.2017.8101976.2017TanzaniaKimei 2017

https://ieeexplore.ieee.org/abstract/document/8101976

EMRBashiri, A., & Ghazisaeedi, M. (2017). Open MRS softwares: effective approaches in management of patients' health information. Int J Commun Med Publ Health, 4(11), 4.2017GlobalBashiri 2017

https://www.researchgate.net/profile/Azadeh-Bashiri/publication/320646470_Open_MRS_softwares_effective_approaches_in_management_of_patients'_health_information/links/5b0021030f7e9be94bd8c8aa/Open-MRS-softwares-effective-approaches-in-management-of-patients-health-information.pdf

EMR
EbolaOza S, Jazayeri D, Teich J, Ball E, Nankubuge P, Rwebembera J, Wing K, Sesay A, Kanter A, Ramos G, Walton D, Cummings R, Checchi F, Fraser H. Development and Deployment of the OpenMRS-Ebola Electronic Health Record System for an Ebola Treatment Center in Sierra Leone
J Med Internet Res 2017;19(8):e294
DOI: 10.2196/jmir.78812017Sierra LeoneOza 2017

https://www.jmir.org/2017/8/e294/

The rapid assembly of a community of designers and developers to build a new tablet based UI and workflow for an Ebola treatment program in Sierra Leone. One of a handful of EHR like applications actually implemented and used for clinical care during the Ebola outbreak. 

Open Source

EMR

Kasthurirathne SN, Mamlin BW, Cullen T. Leveraging the Value of Human Relationships to Improve Health Outcomes. Lessons learned from the OpenMRS Electronic Health Record System. Appl Clin Inform. 2017 Feb 1;8(1):108-121. 

2017GlobalKasthurirathne 2017http://doi.org/10.4338/ACI-2016-08-RA-0139Interoperability
Indicators
Reporting
DHIS2Kariuki, J. M., Manders, E. J., Richards, J., Oluoch, T., Kimanga, D., Wanyee, S., ... & Santas, X. (2016). Automating indicator data reporting from health facility EMR to a national aggregate data system in Kenya: An Interoperability field-test using OpenMRS and DHIS2. Online journal of public health informatics, 8(2).2016KenyaKariuki 2016

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266757/

Patient Outcomes
HIV

Evaluating strategies to improve HIV care outcomes in Kenya: a modelling study.
Olney JJ, Braitstein P, Eaton JW, Sang E, Nyambura M, Kimaiyo S, McRobie E, Hogan JW, Hallett TB.Lancet HIV. 2016 Dec;3(12):e592-e600.
2016KenyaOlney 2016Interoperability
API
EMRKasthurirathne, S. N., Mamlin, B., Kumara, H., Grieve, G., & Biondich, P. (2015). Enabling better interoperability for healthcare: lessons in developing a standards based application programing interface for electronic medical record systems. Journal of medical systems, 39, 1-8.2015GeneralKasthurirathne 2015

https://link.springer.com/article/10.1007/s10916-015-0356-6

Informatics Capacity Building

Building Comprehensive and Sustainable Health Informatics Institutions in Developing Countries: Moi University Experience.
Were MC, Siika A, Ayuo PO, Atwoli L, Esamai F.Stud Health Technol Inform. 2015;216:520-4.
2015Were 2015

Building informatics capacity in Kenya; additional information on AmpathMRS. Per Ampath: "The publications using AMRS have helped us identify key gaps in the HIV care and treatment program including the high rate of LTFU from the first paper we published. We also used AMRS to inform MOH about VL testing in pregnancy a few years ago though this was not published as a paper. More recent use of AMRS data has been in IeDEA analysis that have looked at a number of things including new guideline adoption."

LTFU
HIVGeng EH, Odeny TA, Lyamuya RE, Nakiwogga-Muwanga A, Diero L, Bwana M, Muyindike W, Braitstein P, Somi GR, Kambugu A, Bukusi EA, Wenger M, Wools-Kaloustian KK, Glidden DV, Yiannoutsos CT, Martin J. Estimation of Mortality among HIV-infected people on antiretroviral therapy treatment in east Africa: a sampling based approach in an observational, multisite, cohort study. Lancet HIV. 2015 Mar 1;2(3):e107-e116. PubMed PMID: 26120593; PubMed Central PMCID: PMC4480204.2015Geng 2015Identified LTFU patients to be tracked to help understand what was going on

3233/SHTI240590

2024

Rwanda

Ntakirutimana 2024

https://pubmed.ncbi.nlm.nih.gov/39176970/

Study found the OpenMRS system useful in simplifying patient care and reporting as nurses also could use the system with limited and manageable challenges. . Some barriers related to the use of the system were slowness of the system, turnover of trained users, and some challenges related to system design and navigations.

Water Quality

Epidemiology


Disease Surveillance

Rural

Finkelstein, A. L. (2024). Is Our Water Safe to Drink? A View from Rural Honduras (Publication No. 46199) [Master Essay, University of Pittsburgh].

2024

Rural Honduras

Finkelstein 2024

PDF

Implementation of OpenMRS in San Jose del Negrito, Honduras, for improved disease surveillance and healthcare management. The system is intented to track child growth, prenatal care, and malnutrition and also how they tie to the public water quality.

Implementation

HIV

Interoperability

Maoeng, M., Bruce, K., Motebang, M., Chen, C. W., Lecher, S., Gadisa, T., Saito, S., & Ntsaba, M. (2024). From Disease Specific to Universal Health Coverage in Lesotho: Successes and Challenges Encountered in Lesotho’s Digital Health Journey. Oxford Open Digital Health. DOI:10.1093/oodh/oqae021

2024

Lesotho

Maoeng 2024

PDF

Highlights opportunities & challenges of scaling/expanding from a system ( Based on OpenMRS Bahmni Distro) that was built to serve only HIV & TB needs, to multiple areas to become functional across all reportable diseases. Shows need for Core elements of digital health systems including governance, security, power, & connectivity to be in place.

Implementation

Quality Improvement

HIV

Fraser H, Mugisha M, Bacher I, Ngenzi J, Seebregts C, Umubyeyi A, Condo J. (2024)
Factors Influencing Data Quality in Electronic Health Record Systems in 50 Health Facilities in Rwanda and the Role of Clinical Alerts: Cross-Sectional Observational Study
JMIR Public Health Surveill 2024;10:e49127
DOI: 10.2196/49127

2024

Rwanda

Fraser 2024

https://publichealth.jmir.org/2024/1/e49127

Study on 50 health facilities (HFs) using OpenMRS, an EHR system that supports HIV care in Rwanda, and performed a data quality evaluation

Implementation

Improvement

D. RWEGASIRA et al. (2024), "Deployment and Innovation Processes of Integrated Electronic Medical Record (EMR) System: A Case of University Health Centre Living Lab in Tanzania," 2024 IST-Africa Conference (IST-Africa), Dublin, Ireland, 2024, pp. 1-8, doi: 10.23919/IST-Africa63983.2024.10569206.

2024

Tanzania

Rwegasira 2024

https://ieeexplore.ieee.org/abstract/document/10569206

Challenges identified and development approaches, results, and system implementation benefits, for iCareConnect+, an OpenMRS implementation at University of Dar es Salaam Health Centre living lab.

Maternal Healthcare

M. CHEMISTO et al.(2024). "ICT for Improved Maternal Healthcare in Uganda: A Systematic Literature Review," 2024 IST-Africa Conference (IST-Africa), Dublin, Ireland, 2024, pp. 1-11, doi: 10.23919/IST-Africa63983.2024.10569857.

2024

Uganda

CHEMISTO 2024

https://ieeexplore.ieee.org/abstract/document/10569857

The influence of ICTs on Uganda's maternal health sector development based on the premise that ICTs like OpenMRS, have supported improvements in maternal health services such as antenatal, pregnancy, and postnatal care.

HIV

HIV viral suppression

HIV medication

Implementation

Hedima, E. W., Ohieku, J. D., David, E. A., Ikunaiye, N. Y., Nasir, A., Alfa, M. A., Abubakar S., Bwiyam, I. K., & Bitrus, T. Z. (2024).
Evaluation of viral suppression and medication-related burden among HIV-infected adults in a secondary care facility,
Exploratory Research in Clinical and Social Pharmacy, 2024, 100473, ISSN 2667-2766

2024

Nigeria

Hedima 2024

https://www.sciencedirect.com/science/article/pii/S2667276624000702

Study conducted with data collected using Nigeria-OpenMRS revealed that majority of the patients achieved viral suppression with moderate degree of medication-related burden. Proposed Targeted interventions toward younger patients, females and patients with unsuppressed viral loads

Antenatal Care

Quality improvement

Implementation

Casella Jean-Baptiste M, Vital Julmiste T, Ball E (2024). Health Information System Strengthening During Antenatal Care in Haiti: Continuous Quality Improvement Study
JMIR Form Res 2024;8:e55000
DOI: 10.2196/55000

2024

Haiti

Jean-Baptiste 2024

https://formative.jmir.org/2024/1/e55000

Improved data use and quality for antenatal patient care using OpenMRS at Hôpital Universitaire de Mirebalais (Haiti). Zanmi Lasante and Partners In Health

Interoperability

Standards-based

HL7 FHIR

Bacher I, Goodrich M, Kimaina A, Seaton M, Faulkenberry G, Vaish S, Flowers J, Fraser HS. FHIRing up OpenMRS: Architecture, Implementation and Real-World Use-Cases in Global Health. AMIA Jt Summits Transl Sci Proc. 2024 May 31;2024:162-171. PMID: 38827065; PMCID: PMC11141833.

2024

General

Bacher 2024

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11141833/

Oncology, Cervical Cancer Screening

User Training

Crawford, E., Hebert, K. S., Gaju, S., Mumukunde, I., Dusengimana, J. M. V., & Hagenimana, M. (2024). Lessons From the Design and Rollout of an Electronic Medical Record System for Cervical Cancer Screening in Rwanda. Global Health: Science and Practice.

2024

Rwanda

Crawford 2024

https://doi.org/10.9745/GHSP-D-23-00469

Also provides helpful history of OpenMRS useage in Rwanda.

“OpenMRS uses a data dictionary concept that makes it easy to customize for different disease programs without having to reprogram, making it ideal for low-resource settings that usually have a challenge of technical expertise to support complex programming tasks.”

HIE, Interoperability

Standards-based

Surveillance

HIV

Oluoch, T., Byiringiro, B., Tuyishime, E., Kitema, F., Ntwali, L., Malamba, S., ... & Remera, E. (2024). Implementation of an HIV Case Based Surveillance Using Standards-Based Health Information Exchange in Rwanda. In MEDINFO 2023—The Future Is Accessible (pp. 875-880). IOS Press.

2024

Rwanda

Oluoch 2024

https://doi.org/10.3233/SHTI231090

HIS Leadership

HIS Maturity

eHealth Leaders

Strategy

Vumbugwa, P., Puttkammer, N., Majaha, M., Stampfly, S., Biondich, P., Shivers, J. E., ... & Feldacker, C. (2024). Leveraging Health Information System Maturity Assessments to Guide Strategic Priorities: Perspectives from African Leaders. medRxiv, 2024-02.

2024

General (Africa)

Vumbugwa 2024

https://doi.org/10.1101/2024.02.27.24303453

Extremely helpful quotes from Ministry of Health and HIS sector leaders on the challenges they face. 

Gastroenterology, Hospital

Macatiag IV, J. J., Mariño, B. A. M., Pajes, A. N. N. I., & Yasay, E. B. (2024). Adenoma Detection Rate and Polyp Detection Rate among Gastroenterology Fellows and Consultants in a Tertiary Hospital in the Philippines: A Cross-sectional Study. Acta Medica Philippina.

2024

Philippines

Macatiag 2024

https://doi.org/10.47895/amp.vi0.8395

Data from the OpenMRS system used at a tertiary hospital in the Philippines was used to assess Adenoma and Polyp Detection rates. 

Mental Health

Rural, Urban, Slum

Adult, Adolescent

Kallakuri, S., Gara, S., Godi, M., Yatirajula, S. K., Paslawar, S., Daniel, M., ... & Maulik, P. K. (2024). Learnings From Implementation of Technology-Enabled Mental Health Interventions in India: Implementation Report. JMIR Medical Informatics12, e47504.

2024

India

Kallakuri 2024

https://doi.org/10.2196/47504

Multiple mobile apps were used throughout different contexts (rural, urban; adult, adolescent) in India to evaluate mental health. All tools were actually built on OpenMRS.  

Implementation

Infrastructure

HIV

Njuba, L., Gómez‐Morantes, J. E., Herrera, A., & Camacho, S. (2024). Health information systems in extreme contexts: Using mobile phones to fight AIDS in Uganda. The Electronic Journal of Information Systems in Developing Countries, e12314.

2024

Uganda

Njuba 2024

https://doi.org/10.1002/isd2.12314

Excellent review of how OpenMRS has been used for HIV care in Uganda, and implementation details. 

Insightful Quote: "In the KHCIV ART clinic alone, (before) the OpenMRS (system) was introduced, there was a large room full of paper files of HIV patients missing from care, with only 23% of patients active in the program, meaning that the remaining 77% have been lost in care, died, or migrated."

Privacy

Regulation Compliance

Code Review

Tang, F., & Østvold, B. M. (2024). Finding Privacy-relevant Source Code. arXiv preprint arXiv:2401.07316.

2024

Global

Tang 2024

https://doi.org/10.48550/arXiv.2401.07316

Their study revealed that only 3.9% of the total OpenMRS codebase is made up of methods that are privacy-relevant and involved in personal data processing. This result highlights the precision of their approach in pinpointing privacy-relevant methods in applications.

Open Source eHealth

Haines, N. (2024). Sustainable Translation of Digital Health Technologies. Wellcome Open Res9(19), 19.

2024

Global

Haines 2024

https://doi.org/10.21955/wellcomeopenres.1115374.1

Helpful background on OpenMRS and comparison with other well known Open Source digital health solutions. 

Implementation

Infrastructure

HIV

Lober, W. B., Quiles, C., Wagner, S., Cassagnol, R., Lamothes, R., Alexis, D. R. P., Sutton, P., & Puttkammer, N. Three Years Experience with the Implementation of a Networked Electronic Medical Record in Haiti.

2024

Haiti

Lober 2024

PDF


CyberSecurity

Payment Fraud Prevention

Saranya, A., Naresh, R., Karuppiah, S., & Jenifer, M. (2024). Development of trust-based authorization and authentication framework for secure electronic health payment in cloud environment. Soft Computing, 1-16.

2024

Global

Saranya 2024

https://link.springer.com/article/10.1007/s00500-023-09514-w


Health Information System Strengthening

Continuous Quality Improvement Study

Casella Jean-Baptiste M, Vital Julmiste T, Ball E. (2024) Health Information System Strengthening During Antenatal Care in Haiti: Continuous Quality Improvement Study
JMIR Form Res 2024;8:e55000
DOI: 10.2196/55000

2024

Haiti

Casella 2024

https://formative.jmir.org/2024/1/e55000/

Study on how to improve electronic data collection as well as the transition from paper to electronic documentation within a burgeoning health care systems.

Distributed Software Development

OpenMRS version 1 (O1)

HISP India

Krishna, S. (2023). Challenges and Solutions in Distributed Software Development: A case study from India on Hospital Information System built on OpenMRS framework. Reprosentralen, University of Oslo, Autumn 2023.

2023

India

Krishna 2023

https://www.duo.uio.no/bitstream/handle/10852/108527/5/Srinivas-Krishna-Master-Thesis---Final.pdf

Review of OpenMRS version 1 platform, useage in India by the HISP India team, visits at multiple healthcare sites in India, and challenges faced by software teams engaged in georgraphically distributed software development. 

Health information exchange HIE; Data quality; Viral load

Aniekwe, C., Cuffe, K., Audu, I., Nalda, N., Ibezim, B., Nnakwe, M., ... & Shrivastava, R. (2023). Assessing the effect of electronic health information exchange on the completeness and validity of data for measuring viral load testing turnaround time in Nigeria. International Journal of Medical Informatics, 174, 105059.

2023

Nigeria

Aniekwe 2023

https://doi.org/10.1016/j.ijmedinf.2023.105059

Demonstrated evidence of significant improvement in the quality of data available to measure viral load turnaround time with the implementation of HIE

COVID

HIV

Healthcare Workers

De Schacht C, Nhacule E, Belo C on behalf of the COVIV Study Collaborative Group, et al. Measuring the burden of SARS-CoV-2 infection among persons living with HIV and healthcare workers and its impact on service delivery in Mozambique: protocol of a prospective cohort studyBMJ Open 2023;13:e068988. 

2023

Mozambique

De Schacht 2023

10.1136/bmjopen-2022-068988 


PHC Primary Health Care

Kumar, Rajesh. Application of digital technologies in primary healthcare: Opportunities & challenges. Indian Journal of Medical Research 157(4):p 276-279, April 2023. | DOI: 10.4103/ijmr.ijmr_3056_21 

2023

India

Kumar 2023

10.4103/ijmr.ijmr_3056_21  


Machine Learning

Deduplication

Dixon, A., Thengo, L., Kitsao, E., Matiya, K., Barasa, M., Nyirongo, R., ... & Mbae, S. (2023). Community and Facility Health Information System Integration in Malawi: A Comparison of Machine Learning and Probabilistic Record Linkage Methods. ACM Journal on Computing and Sustainable Societies.

2023

Malawi

Dixon 2023

https://doi.org/10.1145/3624773 


Accessibility

Visual Impairment

Human-Computer Interaction (HCI)

OpenMRS v2

Moncy, M. M., Pilli, M., Somasundaram, M., Purkayastha, S., & Fulton, C. R. (2023). Evaluation of accessibility of open-source EHRs for visually impaired users. arXiv preprint arXiv:2311.02531.

2023

General

Moncy 2023

https://arxiv.org/abs/2311.02531#:~:text=https%3A//doi.org/10.48550/arXiv.2311.02531 


HIV ARV

Retention, Resistance

Joaquim, L., Miranda, M. N., Pimentel, V., Martins, M. D. R. O., Nhampossa, T., Abecasis, A., & Pingarilho, M. (2023). Retention in Care and Virological Failure among Adult HIV-Positive Patients on First-Line Antiretroviral Treatment in Maputo, Mozambique. Viruses, 15(10), 1978.

2023

Mozambique

Joaquim 2023

https://doi.org/10.3390/v15101978 


Anemia / Anaemia

Anton-Vazquez V, Mnzava D, Okuma J, Mlembe S, Lo Riso L, Sanchez JM, et al. (2023) Improving anaemia diagnosis using peripheral blood smear with remote interpretation in adults living with HIV with moderate to severe anaemia: A prospective study nested within the Kilombero and Ulanga antiretroviral cohort. PLoS ONE 18(10): e0293084. 

2023

Tanzania

Anton-Vazquez 2023

https://doi.org/10.1371/journal.pone.0293084


EMR

IPV, GBV

HIV Index Case Testing (ICT)

Mbah, Rogers, Honoré, Ngend. A Review of Index Case Testing Induced Intimate Partner Violence and Electronic Management of Information in HIV Care. xx (2023). 

2023

Cameroon

Mbah 2023

10.4236/etsn.2023.124005 

Recommendations: • Data tools for HIV AIDS should integrate IPV indicators. • Include management of IPV survivors in existing EMR systems. • Develop more comprehensive EMRs that include complete care continua, especially for low-income settings. • Countries with limited resources should consider OPENMRS to implement EMR. • Screening for IPV among HIV patients should be scaled up to reduce IPV incidence. • IPV counseling services should be offered post-HIV test counseling to control IPV incidence rates.

Interoperability

Standards

Mehmood, N.Q., Mahfooz, S.Z., Faroom, S. et al. Usability evaluation of interoperability interfaces in electronic medical record systems. Health Serv Outcomes Res Method (2023). https://doi.org/10.1007/s10742-023-00312-3

2023

General

Mehmood 2023

https://link.springer.com/article/10.1007/s10742-023-00312-3


Open Source

EMR

ICD 10

Capacity Building

Mougou, S. (2023). Building Stronger Healthcare in Tunisia: EHR Implementation with Open Software and Local Capacity Building. In Open Infrastructure Fund/Fondo de Infraestructura Abierta.

2023

Tunisia

Mougou, 2023

https://openreview.net/forum?id=hVPDxT22Ze

Testing three EHR systems to determine their suitability for meeting the requirements discussed by working groups. Assessing the capability to: integrate both clinical data and genomic data; the capacity to incorporate standardized medical vocabulary in both English and French languages; along with its alignment with ICD10 standards

Open Source

Krasodomski-jones, A., & Eaves, D. (2023). Laying the Foundation for the Future: Open Source Sustainability and the Adoption of Digital Public Goods.

2023

General

Krasodomski-jones, 2023

https://policycommons.net/artifacts/3793098/laying-the-foundation-for-the-future/4598925/


Prenatal, ANC
EMR

Prieto-Egido, I., Garrido Madrigal, A., & Barrena García, C. (2023, February). Development and Validation of a Health Information System to Improve Prenatal Controls in Guatemala. In International Congress on Information and Communication Technology (pp. 109-127). Singapore: Springer Nature Singapore.

2023

Guatemala

Prieto-Egido 2023

https://link.springer.com/chapter/10.1007/978-981-99-3091-3_10


CDS
HIV

Magrabi, F., Cresswell, K., & Fraser, H. S. (2023). International dimensions of clinical decision support systems. In Clinical Decision Support and Beyond (pp. 145-188). Content Repository Only!.

2023

Kenya, Rwanda

Magrabi 2023

https://www.sciencedirect.com/science/article/abs/pii/B9780323912006000139


HIV

Mnzava, D., Okuma, J., Ndege, R., Kimera, N., Ntamatungiro, A., Nyuri, A., ... & Weisser, M. (2023). Decentralization of viral load testing to improve HIV care and treatment cascade in rural Tanzania: observational study from the Kilombero and Ulanga Antiretroviral Cohort. BMC Infectious Diseases, 23(1), 222.

2023

Tanzania

Mnzava 2023

https://link.springer.com/article/10.1186/s12879-023-08155-6


Open Source
Software Architecture, Architectural Smells, Software Performance

Arcelli Fontana, F., Camilli, M., Rendina, D., Taraboi, A. G., & Trubiani, C. (2023, June). Impact of Architectural Smells on Software Performance: an Exploratory Study. In Proceedings of the 27th International Conference on Evaluation and Assessment in Software Engineering (pp. 22-31).

2023

General
Team from: Italy

Fontana 2023

https://dl.acm.org/doi/pdf/10.1145/3593434.3593442


Thyroid Cancer
Ultrasound
Oncology

Bisquera, Valparaiso, Perez, Uy, Espiritu, Pialago, Clarit. A Single Institution Experience on the Correlation of Kwak Thyroid Imaging Reporting and Data System Score (Kwak TIRADS) and Malignancy of Thyroid Nodules seen in a Tertiary Hospital Setting. World Cancer Research Journal, 10, e2498.

2023

Philippines

Bisquera 2023

https://www.wcrj.net/article/2498


Medical Training

Capacity Building

Stephanie Medlock, Kim J. Ploegmakers, Ronald Cornet, Kim Win Pang, Use of an open-source electronic health record to establish a “virtual hospital”: A tale of two curricula, International Journal of Medical Informatics, Volume 169, 2023, 104907, ISSN 1386-5056, https://doi.org/10.1016/j.ijmedinf.2022.104907.

2023

Netherlands

Medlock 2023

https://www.sciencedirect.com/science/article/pii/S1386505622002210


COVID
Home monitoring

Sikder, A., Dickhoner, J., Kysh, L., Musheghyan, L., Shekherdimian, S., Levine, B., & Espinoza, J. (2022). International Collaboration to Develop a Remote Monitoring Web App for COVID-19 Patients in Armenia: Design and Development With Agile Methodology. JMIR Human Factors, 9(4), e40110.

2022

Armenia

Sikder 2022

https://europepmc.org/article/med/36350739

The software was designed and developed over 2 months using human-centered design and agile sprints. Once live, 5087 patient records were created for 439 unique patients.

HIV
ART
Disease Survillance

Fataha, N. V. F. A., Gaveta, S., Langa, J. C., Banze, A. R., Sacarlal, J., Rossetto, E. V., ... & Kellogg, T. A. (2022). Evaluation of the Mozambique Antiretroviral Therapy (MozART) database as an antiretroviral therapy patient surveillance system, 2017-2018. The Pan African Medical Journal, 42.

2022

Mozambique

Fataha 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9429983/



COVID

Mirza, Muzna, Yoran Grant-Greene, Marie PJS Valles, Patrice Joseph, Stanley Juin, Stephan Brice, Patrick Dely et al. "Leveraging PEPFAR-supported health information systems for COVID-19 pandemic response." Emerging Infectious Diseases 28, no. Suppl 1 (2022): S49.

2022

Haiti

Mirza 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9745247/


Tuberculosis

Siamisang, K., Rankgoane-Pono, G., Madisa, T. M., Mudiayi, T., & Tlhakanelo, J. T. (2022). Outcomes and predictors of tuberculosis mortality in Kweneng West District, Botswana: a retrospective cohort study. The Pan African Medical Journal, 42.

2022

Botswana

Siamisang 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9142783/


OMOP

Espinoza, J., Sikder, A., Lulejian, A., & Levine, B. (2022). Development of an OpenMRS-OMOP ETL tool to support informatics research and collaboration in LMICS. Available at SSRN 4075625.

2022

General

Espinoza 2022

https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4075625


Public Health
Open Source

Wanger, J., Cullen, T., Dunbar, E. L., & Flowers, J. L. (2023). Open-source software for public health: opportunities and approaches. Sexually Transmitted Diseases, 50(8), S31.

2022

General

Wanger 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348654/


HIV
ART

Kisaka, A. M. (2022). Test and treat policy: Effect on ART initiation and retention and health system barriers and facilitators to implementation in AHF Uganda Cares Clinics in Central Uganda (Doctoral dissertation, Makerere University).

2022

Uganda

Kisaka 2022

http://dspace.mak.ac.ug/handle/10570/10866

Results: The 30-days initiation rate was 62.7% before and 90.8% after the T&T policy rollout.

CDS

Fraser, H. S., Mugisha, M., Remera, E., Ngenzi, J. L., Richards, J., Santas, X., ... & Umubyeyi, A. (2022). User perceptions and use of an enhanced electronic health record in Rwanda with and without clinical alerts: cross-sectional survey. JMIR Medical Informatics, 10(5), e32305.

2022

Rwanda

Fraser 2022

https://medinform.jmir.org/2022/5/e32305/

A survey of user experience of a well established HIV implementation by the Rwanda MOH. Part of a larger OpenMRS research study of 112 health facilities in Rwanda.
The EHR top uses were to access client data easily or quickly (62/90, 69%), update patient records (56/89, 63%), create new patient records (49/88, 56%), generate various reports (38/85, 45%), and review previous records (43/89, 48%). In addition, >90% (81/90) of respondents agreed that the EHR made it easier to make informed decisions, was worth using, and has improved patient information quality. .... In intervention sites, staff were significantly more likely to update existing records (P=.04), generate summaries before (P<.001) or during visits (P=.01)

Maternity
Labor, Delivery

Dinh, N., Agarwal, S., Avery, L., Ponnappan, P., Chelangat, J., Amendola, P., ... & Bartlett, L. (2022). Implementation Outcomes Assessment of a Digital Clinical Support Tool for Intrapartum Care in Rural Kenya: Observational Analysis. JMIR Formative Research, 6(6), e34741.

2022

Kenya

Dinh 2022

https://formative.jmir.org/2022/6/e34741

An example of the use of the VecnaCARES maternal child health package using OpenMRS and their custom hardware package for sites with no infrastructure.

HIV
Adolescent

Ahimbisibwe, J. (2022). Factors associated with adherence to Anti-Retroviral Therapy (ART) among adolescents attending HIV clinic at China-Uganda Friendship Hospital-Naguru, Uganda (Doctoral dissertation, Makerere University).

2022

Uganda

Ahimbisibwe 2022

http://dspace.mak.ac.ug/handle/10570/10513


NTD


Ochoa, Rodrigo, Álvarez, Alessa, Freitas, Jordan, Purkayastha, Saptarshi, & Vélez, Iván D.. (2022). NTD Health: An electronic medical record system for neglected tropical diseases. Biomédica42(4), 602-610. Epub December 01, 2022.https://doi.org/10.7705/biomedica.6269

2022

Colombia

Ochoa 2022

http://www.scielo.org.co/scielo.php?pid=S0120-41572022000400602&script=sci_arttext&tlng=en


Open Source

Paton C, Braa J, Muhire A, Marco-Ruiz L, Kobayashi S, Fraser H, Falcón L, Marcelo A. Open Source Digital Health Software for Resilient, Accessible and Equitable Healthcare Systems. Yearb Med Inform. 2022 Aug;31(1):67-73. doi: 10.1055/s-0042-1742508. Epub 2022 Jun 2. PMID: 35654431; PMCID: PMC9719763.

2022

Global

Paton 2022

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9719763


Maternity
PMTCT
HEI
Mentor Mothers

Carlucci, J. G., Yu Z., Gonzalez P., Bravo M., Amorim G., das Felicidades Cugara, C., Guambe, H., Mucanhenga, J., Silva, W., Tique, J. A., Alvim, M. F. S., Graves, E., De Schact, C., Wester, W. The Effect of a Mentor Mothers Program on Maternal and Infant PMTCT Outcomes in Zambézia Province, Mozambique.

2021

Mozambique

Carlucci 2023

https://www.vumc.org/friends-in-global-health/sites/default/files/public_files/docs/11.%20VUMC-FGH_MM_Final%20Report%20ESoP%20Final%20Report_revised_18Nov2021_clean.pdf


EMR
Global Goods
Open Source

Verma N, Mamlin B, Flowers J, Acharya S, Labrique A, Cullen T. OpenMRS as a global good: Impact, opportunities, challenges, and lessons learned from fifteen years of implementation. Int J Med Inform. 2021 May;149:104405. doi: 10.1016/j.ijmedinf.2021.104405. Epub 2021 Feb 5. PMID: 33639327.

2021

Global

Verma 2021

https://pubmed.ncbi.nlm.nih.gov/33639327/


Implementation
EMR
Emergency

Mamlin, Burke W., Jennifer E. Shivers, Nancy K. Glober, and Jonathan J. Dick. "OpenMRS as an emergency EMR—How we used a global good to create an emergency EMR in a week." International Journal of Medical Informatics 149 (2021): 104433.

2021

USA

Mamlin 2021

https://www.sciencedirect.com/science/article/pii/S1386505621000599


AI / ML (Artificial intelligence, Machine Learning)

Epilepsy Diagnosis

Automation

Molina, E., Sarmiento Torres, C. E., Salazar-Cabrera, R., López, D. M., & Vargas-Cañas, R. (2020). Intelligent Telehealth System To Support Epilepsy Diagnosis. Journal of Multidisciplinary Healthcare, 13, 433–445. https://doi.org/10.2147/JMDH.S247878

2020

Columbia, Global

Molina 2020

https://www.tandfonline.com/doi/full/10.2147/JMDH.S247878

Enhancing access to epilepsy care, particularly in areas with few neurologists by reducing review time by 65-75%, and also improving accuracy of EEG diagnosis and data management.

Implementation

Cost analysis

Open Source

Balugaba, B. E., Ruttoh, S. K., Ekirapa, E. K., Siika, A. A., & Were, M. C. (2020). Cost analysis of an electronic medical record system at an urban clinic in Kampala, Uganda. Journal of Health Informatics in Africa, 6(2), 84-89. https://doi.org/10.12856/JHIA-2019-v6-i2-260

2020

Uganda

Balugaba 2020

https://jhia-online.org/index.php/jhia/article/view/260

A comprehensive cost analysis for developing, implementing and maintaining an EMRS (OpenMRS) in a resource-constrained setting to highlight how establishing costs is crucial for sound decision-making regarding allocation of scarce resources.

ICD 11
API

Mugisha, M., Byiringiro, J. B., Uwase, M., Abizeyimana, T., Ndikubwimana, B., Karema, N., ... & Tumusiime, D. (2020). Integration of International Classification of Diseases version 11 application program interface (API) in the Rwandan electronic medical records (openMRS): findings from two district hospitals in Rwanda. In The Importance of Health Informatics in Public Health during a Pandemic (pp. 280-283). IOS Press.

2020

Rwanda

Mugisha 2020

https://ebooks.iospress.nl/doi/10.3233/SHTI200549

Michael Mugisha and colleague carry out research and implementation work with OpenMRS in Rwanda.

Machine Learning
HIV

Comparison of machine learning methods for predicting viral failure: a case study using electronic health record data.
Kimaina A, Dick J, DeLong A, Chrysanthopoulou SA, Kantor R, Hogan JW.Stat Commun Infect Dis. 2020 Nov 12;12(Suppl1):20190017.

2020


Kimaina 2020


Translation of AMRS-based research for improving patient care.

This study was one of the precursors for a large research study on the use of machine learning to improve loss to follow up of HIV patients in Kenya 

Oncology
Chemotherapy

Kabukye, J. K., Casaceli, A. M., Ball, E., De Armas, M., & Cornet, R. (2019). Towards an open-source oncology electronic medical records system for low-resource settings: development of chemotherapy management in OpenMRS. In MEDINFO 2019: Health and Wellbeing e-Networks for All (pp. 634-638). IOS Press.

2019

Uganda
Malawi
Rwanda
Haiti
USA

Kabukye 2019

https://ebooks.iospress.nl/doi/10.3233/SHTI190300


Interoperability

Patient Transfer

Rweikiza, G., & Machuve, D. (2019). Development of medical records exchange system-a case of OpenMRS and Care2X. International Journal of Advanced Technology and Engineering Exploration, 6(52), 77-83.

2019

Tanzania

Rweikiza 2019

https://www.accentsjournals.org/paperInfo.php?journalPaperId=1123

PDF


Diabetes

Yandrapalli, B. T., Jones, J., & Purkayastha, S. (2019). Development and Implementation of a Dashboard for Diabetes Care Management in OpenMRS. arXiv preprint arXiv:1910.11437.

2019

General

Yandrapalli 2019

https://arxiv.org/abs/1910.11437

https://arxiv.org/pdf/1910.11437.pdf


HIV

Humphrey JM, Genberg BL, Keter A, Musick B, Apondi E, Gardner A, Hogan JW, Wools-Kaloustian K. Viral suppression among children and their caregivers living with HIV in western Kenya. J Int AIDS Soc. 2019 Apr;22(4):e25272. doi: 10.1002/jia2.25272. PubMed PMID: 30983148; PubMed Central PMCID: PMC6462809.

2019

Kenya

Humphrey 2018


Helped understand the link between parental viral suppression and child suppression

Radiology, RIS

Gichoya, J. W., Kohli, M., Ivange, L., Schmidt, T. S., & Purkayastha, S. (2018). A platform for innovation and standards evaluation: a case study from the OpenMRS open-source radiology information system. Journal of digital imaging, 31, 361-370.

2018

General

Gichoya 2018

https://link.springer.com/article/10.1007/s10278-018-0088-5


HIV
MCH
LTFU

Holmes CB, Yiannoutsos CT, Elul B, Bukusi E, Ssali J, Kambugu A, Musick BS, Cohen C, Williams C, Diero L, Padian N, Wools-Kaloustian KK. Increased prevalence of pregnancy and comparative risk of program attrition among individuals starting HIV treatment in East Africa. PLoS One. 2018 Jan 17;13(1):e0190828. doi: 10.1371/journal.pone.0190828. eCollection 2018. PubMed PMID: 29342180.

2018


Holmes 2018


Helped understand the impact of pregnancy and sex on retention in care

HIV
Drug Resistance
Pediatric

Wools-Kaloustian K, Marete I, Ayaya S, Sohn AH, Van Nguyen L, Li S, Leroy V, Musick BS, Newman JE, Edmonds A, Davies MA, Eboua FT, Obama MT, Yotebieng M, Sawry S, Mofenson LM, Yiannoutsos CT. Time to First-Line ART Failure and Time to Second-Line ART Switch in the IeDEA Pediatric Cohort. Journal of acquired immune deficiency syndromes. 2018; PubMed [journal] PMID: 29509590

2018


Wools-Kaloustian 2018


Helped identify delays in switching failed regimens.

EMR
Open Source

Syzdykova A, Malta A, Zolfo M, Diro E, Oliveira JL. Open-Source Electronic Health Record Systems for Low-Resource Settings: Systematic Review. JMIR Med Inform. 2017 Nov 13;5(4):e44. doi: 10.2196/medinform.8131. PMID: 29133283; PMCID: PMC5703976.

2017

General

Syzdykova 2017

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5703976/


ANC, MCH

E. Kimei and K. Kalegele, "Digitization of antenatal health card and integration with OpenMRS platform: System analysis and design," 2017 IST-Africa Week Conference (IST-Africa), Windhoek, Namibia, 2017, pp. 1-7, doi: 10.23919/ISTAFRICA.2017.8101976.

2017

Tanzania

Kimei 2017

https://ieeexplore.ieee.org/abstract/document/8101976


EMR

Bashiri, A., & Ghazisaeedi, M. (2017). Open MRS softwares: effective approaches in management of patients' health information. Int J Commun Med Publ Health, 4(11), 4.

2017

Global

Bashiri 2017

https://www.researchgate.net/profile/Azadeh-Bashiri/publication/320646470_Open_MRS_softwares_effective_approaches_in_management_of_patients'_health_information/links/5b0021030f7e9be94bd8c8aa/Open-MRS-softwares-effective-approaches-in-management-of-patients-health-information.pdf


EMR
Ebola

Oza S, Jazayeri D, Teich J, Ball E, Nankubuge P, Rwebembera J, Wing K, Sesay A, Kanter A, Ramos G, Walton D, Cummings R, Checchi F, Fraser H. Development and Deployment of the OpenMRS-Ebola Electronic Health Record System for an Ebola Treatment Center in Sierra Leone
J Med Internet Res 2017;19(8):e294
DOI: 10.2196/jmir.7881

2017

Sierra Leone

Oza 2017

https://www.jmir.org/2017/8/e294/

The rapid assembly of a community of designers and developers to build a new tablet based UI and workflow for an Ebola treatment program in Sierra Leone. One of a handful of EHR like applications actually implemented and used for clinical care during the Ebola outbreak. 

Open Source

EMR

Kasthurirathne SN, Mamlin BW, Cullen T. Leveraging the Value of Human Relationships to Improve Health Outcomes. Lessons learned from the OpenMRS Electronic Health Record System. Appl Clin Inform. 2017 Feb 1;8(1):108-121. 

2017

Global

Kasthurirathne 2017

http://doi.org/10.4338/ACI-2016-08-RA-0139


Cyber Security

Audit Logging

Amir-Mohammadian, S., Chong, S., Skalka, C. (2016). Correct Audit Logging: Theory and Practice. In: Piessens, F., Viganò, L. (eds) Principles of Security and Trust. POST 2016. Lecture Notes in Computer Science(), vol 9635. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-49635-0_8

2016

Global

Amir-Mohammadian 2016

https://link.springer.com/chapter/10.1007/978-3-662-49635-0_8

The paper focuses on enhancing cyber security in systems like OpenMRS by proposing accurate and reliable audit logs through automated program rewriting.

Interoperability
Indicators
Reporting
DHIS2

Kariuki, J. M., Manders, E. J., Richards, J., Oluoch, T., Kimanga, D., Wanyee, S., ... & Santas, X. (2016). Automating indicator data reporting from health facility EMR to a national aggregate data system in Kenya: An Interoperability field-test using OpenMRS and DHIS2. Online journal of public health informatics, 8(2).

2016

Kenya

Kariuki 2016

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266757/


Patient Outcomes
HIV

Evaluating strategies to improve HIV care outcomes in Kenya: a modelling study.
Olney JJ, Braitstein P, Eaton JW, Sang E, Nyambura M, Kimaiyo S, McRobie E, Hogan JW, Hallett TB.Lancet HIV. 2016 Dec;3(12):e592-e600.

2016

Kenya

Olney 2016



Interoperability
API
EMR

Kasthurirathne, S. N., Mamlin, B., Kumara, H., Grieve, G., & Biondich, P. (2015). Enabling better interoperability for healthcare: lessons in developing a standards based application programing interface for electronic medical record systems. Journal of medical systems, 39, 1-8.

2015

General

Kasthurirathne 2015

https://link.springer.com/article/10.1007/s10916-015-0356-6


Informatics Capacity Building

Building Comprehensive and Sustainable Health Informatics Institutions in Developing Countries: Moi University Experience.
Were MC, Siika A, Ayuo PO, Atwoli L, Esamai F.Stud Health Technol Inform. 2015;216:520-4.

2015


Were 2015


Building informatics capacity in Kenya; additional information on AmpathMRS. Per Ampath: "The publications using AMRS have helped us identify key gaps in the HIV care and treatment program including the high rate of LTFU from the first paper we published. We also used AMRS to inform MOH about VL testing in pregnancy a few years ago though this was not published as a paper. More recent use of AMRS data has been in IeDEA analysis that have looked at a number of things including new guideline adoption."

LTFU
HIV

Geng EH, Odeny TA, Lyamuya RE, Nakiwogga-Muwanga A, Diero L, Bwana M, Muyindike W, Braitstein P, Somi GR, Kambugu A, Bukusi EA, Wenger M, Wools-Kaloustian KK, Glidden DV, Yiannoutsos CT, Martin J. Estimation of Mortality among HIV-infected people on antiretroviral therapy treatment in east Africa: a sampling based approach in an observational, multisite, cohort study. Lancet HIV. 2015 Mar 1;2(3):e107-e116. PubMed PMID: 26120593; PubMed Central PMCID: PMC4480204.

2015


Geng 2015


Identified LTFU patients to be tracked to help understand what was going on.

Remote Monitoring

Mobile (m-Health)

Cardiac Health Monitoring

Zhu, T., Osipov, M., Papastylianou, T., Oster, J., Clifton, D. A., & Clifford, G. D. (2014). An intelligent cardiac health monitoring and review system. In Appropriate Healthcare Technologies for Low Resource Settings (AHT 2014) (pp. 1-4). Institution of Engineering and Technology. https://doi.org/10.1049/cp.2014.0785

2014

Global

Zhu 2014

https://ieeexplore.ieee.org/abstract/document/7083597 or
PDF

Cardiovascular disease monitoring using OpenMRS and SanaMobile on Mobile Devices using Remote signals

Immunization

Integration

HIE

Vawdrey, D. K., Natarajan, K., Kanter, A. S., Hripcsak, G., Kuperman, G. J., & Stockwell, M. S. (2013). Informatics lessons from using a novel immunization information system. In C. U. Lehmann et al. (Eds.), MEDINFO 2013 (pp. 589-593). IOS Press. https://doi.org/10.3233/978-1-61499-289-9-589

2013

New York, Tanzania

Vawdrey 2013

https://ebooks.iospress.nl/doi/10.3233/978-1-61499-289-9-589

Use of OpenMRS intergration with EzVac system to improve immunization management.

Informatics Capacity Building

"These are good problems to have…": establishing a collaborative research partnership in East Africa.
Tierney WM, Nyandiko WN, Siika AM, Wools-Kaloustian K, Sidle JE, Kiplagat J, Bell A, Inui TS.J Gen Intern Med. 2013 Sep;28 Suppl 3(Suppl 3):S625-38.

2013


Tierney 2013

https://pubmed.ncbi.nlm.nih.gov/23797916/

Building informatics capacity in Kenya; additional information on AmpathMRS

Decision Support (CDS)
Pediatrics
HIV

Computer-generated reminders and quality of pediatric HIV care in a resource-limited setting.
Were MC, Nyandiko WM, Huang KT, Slaven JE, Shen C, Tierney WM, Vreeman RC.Pediatrics. 2013 Mar;131(3):e789-96.

2013


Were 2013


One of the most important clinical evaluation studies of the  impact of OpenMRS in improving care.

EMR

Open Source

Modular

Kasthurirathne, S. N. (2012). Designing and developing an open source medical informatics module. XRDS: Crossroads 19(2), 20-23. doi:10.1145/2382856.

2382866 

2382866 

2012


Kasthurirathne 2012

http://dl.acm.org/citation.cfm?id=2382866


Open Source

de Abajo, B. S., & Ballestero, A. L. (2012). Overview of the most important open source software: analysis of the benefits of OpenMRS, OpenEMR, and VistA. In Telemedicine and e-health services, policies, and applications: Advancements and developments (pp. 315-346). IGI Global.

2012

General

de Abajo 2012

https://www.igi-global.com/chapter/content/64993


Implementation
EMR
Open Source

Mohammed-Rajput NA, Smith DC, Mamlin B, Biondich P, Doebbeling BN; Open MRS Collaborative Investigators. OpenMRS, a global medical records system collaborative: factors influencing successful implementation. AMIA Annu Symp Proc. 2011;2011:960-8. Epub 2011 Oct 22. PMID: 22195155; PMCID: PMC3243141.

2011

Global

Mohammed-Rajput 2011

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243141/


Terminology
SNOMED
Tuberculosis

Halland, K., & Britz, K. (2011). Investigations into the use of SNOMED CT to enhance an OpenMRS health information system. South African Computer Journal, 47(1), 33-45.

2011

South Africa

Halland 2011

https://journals.co.za/doi/abs/10.10520

/EJC28115

Decision Support (CDS)
HIV

Evaluation of computer-generated reminders to improve CD4 laboratory monitoring in sub-Saharan Africa: a prospective comparative study.
Were MC, Shen C, Tierney WM, Mamlin JJ, Biondich PG, Li X, Kimaiyo S, Mamlin BW.J Am Med Inform Assoc. 2011 Mar-Apr;18(2):150-5.
2011Were 2011Early clinical evaluation of the impact of OpenMRS (paper based) reminders on patient care

/EJC28115


Decision Support (CDS)
HIV

Evaluation of computer-generated reminders to improve CD4 laboratory monitoring in sub-Saharan Africa: a prospective comparative study.
Were MC, Shen C, Tierney WM, Mamlin JJ, Biondich PG, Li X, Kimaiyo S, Mamlin BW.J Am Med Inform Assoc. 2011 Mar-Apr;18(2):150-5.

2011


Were 2011


Early clinical evaluation of the impact of OpenMRS (paper based) reminders on patient care

Education

Training

Software

Implementation

Seymour, R. P., Tang, A., DeRiggi, J., Munyaburanga, C., Cuckovitch, R., Nyirishema, P., & Fraser, H. S. F. (2010). Training software developers for electronic medical records in Rwanda. In C. Safran et al. (Eds.), MEDINFO 2010 (Vol. 160, pp. 585-589). IOS Press. https://doi.org/10.3233/978-1-60750-588-4-585

2010

Rwanda

Seymour 2010

https://ebooks.iospress.nl/volumearticle/13505

Highlights of a training course created to provide high-quality Rwandan software developers with the necessary programming skills and grasp of medical informatics to contribute the implementation of OpenMRS.

HIV

Manders, E. J., José, E., Solis, M., Burlison, J., Nhampossa, J. L., & Moon, T. (2010). Implementing OpenMRS for patient monitoring in an HIV/AIDS care and treatment program in rural Mozambique. In MEDINFO 2010 (pp. 411-415). IOS Press.

2010

Mozambique

Manders 2010



MCH
Reproductive Health

Thompson, A., Castle, E., Lubeck, P., & Makarfi, P. S. (2010). Experience implementing OpenMRS to support maternal and reproductive health in Northern Nigeria. In MEDINFO 2010 (pp. 332-336). IOS Press.

2010

Nigeria

Thompson 2010

https://ebooks.iospress.nl/volumearticle/13451

Early implementation of OpenMRS for maternal-child health

Implementation

Tierney, W. M., Achieng, M., Baker, E., Bell, A., Biondich, P., Braitstein, P., ... & Tanzania-Uganda OpenMRS Consortium. (2010). Experience implementing electronic health records in three East African countries. In MEDINFO 2010 (pp. 371-375). IOS press.

2010

Tanzania
Uganda
Kenya

Tierney 2010

https://ebooks.iospress.nl/doi/10.3233/978-1-60750-588-4-371


Implementation
Capacity Building

Seebregts, C. J., Mamlin, B. W., Biondich, P. G., Fraser, H. S. F., Wolfe, B. A., Jazayeri, D., ... & Kanter, A. S. (2010). Human factors for capacity building. Lessons learned from the OpenMRS implementers network. Yearbook of medical informatics, 19(01), 13-20.

2010

Global

Seebregts 2010

https://www.thieme-connect.com/products/ejournals/html/10.1055/s-0038-1638681

A second paper on the openMRS implementors and community

HIV

Braitstein P, Ayuo P, Mwangi A, Wools-Kaloustian K, Musick B, Siika A, Kimaiyo S. Sustainability of first-line antiretroviral regimens: findings from a large HIV treatment program in western Kenya. Journal of acquired immune deficiency syndromes. 2010;53(2):254-259.

2010

Kenya

Braitstein 2010


Helped look at sustainability of firstline regimens

PMTCT
HIV
MCH

Nyandiko WM, Otieno-Nyunya B, Musick B, Bucher-Yiannoutsos S, Akhaabi P, Lane K, Yiannoutsos CT, Wools-Kaloustian K. Outcomes of HIV-exposed children in western Kenya: efficacy of prevention of mother to child transmission in a resource-constrained setting. Journal of acquired immune deficiency syndromes. 2010;54(1):42-50.

2010

Kenya

Nyandiko 2010


Helped assess the effectiveness of the PMTCT program.

EMR
Open Source

Christopher J. Seebregts, Burke W. Mamlin, Paul G. Biondich, Hamish S.F. Fraser, Benjamin A. Wolfe, Darius Jazayeri, Christian Allen, Justin Miranda, Elaine Baker, Nicholas Musinguzi, Daniel Kayiwa, Carl Fourie, Neal Lesh, Andrew Kanter, Constantin T. Yiannoutsos, Christopher Bailey,
The OpenMRS Implementers Network, International Journal of Medical Informatics, Volume 78, Issue 11, 2009, Pages 711-720, ISSN 1386-5056, https://doi.org/10.1016/j.ijmedinf.2008.09.005.

2009

Global

Seebregts, 2009

https://www.sciencedirect.com/science/article/abs/pii/S1386505608001652

Important early paper on OpenMRS community with Chris Seebregts one of the 4 co-founders as first author.

Implementation
HIV

Allen, C., Jazayeri, D., Miranda, J., Biondich, P. G., Mamlin, B. W., Wolfe, B. A., ... & Fraser, H. S. (2007). Experience in implementing the OpenMRS medical record system to support HIV treatment in Rwanda. Studies in health technology and informatics, 129(1), 382.

2007

Rwanda

Allen 2007

https://books.google.ca/books?hl=en&lr=&id=KAnvAgAAQBAJ&oi=fnd&pg=PA382&dq=openmrs&ots=Uv2VU-P_-h&sig=IhgD3kpiqiA4_NhdNb2KTlo60HU&redir_esc=y#v=onepage&q=openmrs&f=false

Early work with OpenMRS in Rwanda

EMR

Nutrition

Rural

Allen C, Manyika P, Ufitamahoro E, Musabende A, Rich M, Jazayeri D, Fraser H. Expanding an electronic medical record to support community health worker and nutritional support programs in rural Rwanda. AMIA Annual Symposium Proceedings.

 2007

 2007 Oct 11:860.

2007

Rwanda

Allen 2007


Early work with OpenMRS in Rwanda

Tuberculosis

Labs

Blaya JA, Shin SS, Yagui MJ, Yale G, Suarez CZ, Asencios LL, Cegielski JP, Fraser HS. A web-based laboratory information system to improve quality of care of tuberculosis patients in Peru: functional requirements, implementation and usage statistics. BMC Medical Informatics and Decision Making.

 2007

 2007 Oct 28;7:33. 

2007

Peru

Blaya 2007

http://www.ncbi.nlm.nih.gov/pubmed/17963522


EMR

The AMPATH medical record system: creating, implementing, and sustaining an electronic medical record system to support HIV/AIDS care in western Kenya.
Tierney WM, Rotich JK, Hannan TJ, Siika AM, Biondich PG, Mamlin BW, Nyandiko WM, Kimaiyo S, Wools-Kaloustian K, Sidle JE, Simiyu C, Kigotho E, Musick B, Mamlin JJ, Einterz RM.Stud Health Technol Inform. 2007;129(Pt 1):372-6.

2007

Kenya

Tierney 2007


General background on the early days of OpenMRS, it's precursor system and AmpathMRS.

EMR

HIV

Allen C, Manyika P, Jazayeri D, Rich M, Lesh N, Fraser H. Rapid deployment of electronic medical records for ARV rollout in rural Rwanda. AMIA Annual Symposium Proceedings.

 2006

 2006:840. 

2006

Rwanda

Allen 2006

http://www.ncbi.nlm.nih.gov/pubmed/17238460

The first paper describing the OpenMRS work in Rwanda. 

EMR
Open Source

Wolfe BA, Mamlin BW, Biondich PG, Fraser HS, Jazayeri D, Allen C, Miranda J, Tierney WM. The OpenMRS system: collaborating toward an open source EMR for developing countries. AMIA Annu Symp Proc. 2006;2006:1146. PMID: 17238765; PMCID: PMC1839362.

2006

Global

Wolfe 2006

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1839362/

Post version of the previous paper in the first year.

EMR
Open Source

Mamlin BW, Biondich PG, Wolfe BA, Fraser H, Jazayeri D, Allen C, Miranda J, Tierney WM. Cooking up an open source EMR for developing countries: OpenMRS - a recipe for successful collaboration. AMIA Annu Symp Proc. 2006;2006:529-33. PMID: 17238397; PMCID: PMC1839638.

2006

Global

Mamlin 2006

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1839638/

The first OpenMRS paper the year we first launched in Kenya, Rwanda and South Africa. 

HIV
LTFU

Wools-Kaloustian K, Kimaiyo S, Diero L, Siika A, Sidle J, Yiannoutsos CT, Musick B, Einterz R, Fife KH, Tierney WM. Viability and effectiveness of large-scale HIV treatment initiatives in sub-Saharan Africa: experience from western Kenya. Aids. 2006;20(1):41-48.

2006

Kenya

Wools-Kaloustian 2006


Identified LTFU as an issue

EMR

AMPATH Medical Record System (AMRS): collaborating toward an EMR for developing countries.
Mamlin BW, Biondich PG.AMIA Annu Symp Proc. 2005;2005:490-4.

2005

Kenya

Mamlin 2005

https://pubmed.ncbi.nlm.nih.gov/16779088/

General background on the early days of OpenMRS describing one of the two precursor systems.

EMR

Biondich PG, Mamlin BW, Hannan TJ, Tierney WM. A Call For Collaboration: Building an EMR for Developing Countries.  AMIA Annual Symposium; 2005; Washington, D.C.; 2005. 

2005

Global

Biondich 2005

https://www.ncbi.nlm.nih.gov/pubmed/16779181

OpenMRS design and development underway

EMR

Fraser H, Biondich P, Moodley D, Choi S, Mamlin B, Szolovits P. Implementing electronic medical record systems in developing countries. Informatics in Primary Care. 2005;13:83-95. 

2005

Global

Fraser 2005

https://www.ncbi.nlm.nih.gov/pubmed/15992493

Early designs and EHR projects in low income settings. Kind of a manifesto for OpenMRS design and use. Strangely has masses of citations even to this day...

EMR

(Early days)

Rotich JK, Hannan TJ, Smith FE, Bii J, Odero WW, Vu N, Mamlin BW, Mamlin JJ, Einterz RM, Tierney WM. Installing and implementing a computer-based patient record system in sub-Saharan Africa: the Mosoriot Medical Record System. J Am Med Inform Assoc. 2003 Jul-Aug;10(4):295-303. doi: 10.1197/jamia.M1301. Epub 2003 Mar 28. PMID: 12668697; PMCID: PMC181978.

2003

Kenya

Rotich 2003

https://pubmed.ncbi.nlm.nih.gov/12668697/

This described the main precursor system of OpenMRS at AMPATH

EMR

(Early days)

Tierney WM, Rotich JK, Smith FE, Bii J, Einterz RM, Hannan TJ. Crossing the "digital divide:" Implementing an electronic medical record system in a rural Kenyan health center to support clinical care and research. Proc AMIA Symp

 2002

 2002: 792-795. 

2002

Kenya

Tierney 2002

http://www.ncbi.nlm.nih.gov/pubmed/12463933

This described the main precursor system of OpenMRS at AMPATH

EMR

(Early days)

Hannan TJ, Tierney WM, Rotich JK, Odero WW, Smith F, Mamlin JJ, Einterz RM. The MOSORIOT medical record system (MMRS) phase I to phase II implementation: an outpatient computer-based medical record system in rural Kenya. Medinfo.

 2001

 2001; 10(Pt 1):619-22. 

2001

Kenya

Hannan 2001

http://www.ncbi.nlm.nih.gov/pubmed/11604811

This described the main precursor system of OpenMRS at AMPATH