OpenMRS Evidence Hub
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This page is our online repository of the many studies conducted exploring OpenMRS. Collectively, these studies provide strong evidence for a variety of use cases: the impact of EMR use on care, secondary data use for site or regional or global program guidelines improvement, and the community open source model. The OpenMRS Community maintains the OpenMRS Evidence Base and adds new studies as they are discovered.
Over 4,300 publications are noted online involving OpenMRS - search query here.
Note
This page began in August 2023. We are communally updating this with the thousands of articles published on OpenMRS, strongly prioritizing recent articles from within the last few years.
Category | Citation APA formatting preferred | Year | Country | Reference Key | URL | Misc. Notes |
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Implementation | Elepaño, A., Tan‑Lim, C. S., Javelosa, M. A., De Mesa, R. Y., Rey, M., Sanchez, J., Dans, L., & Dans, A. M. (2025, July 15). Implementing Electronic Health Records in Philippine Primary Care Settings: Mixed‑Methods Pilot Study. JMIR Medical Informatics, 13, e63036. https://doi.org/10.2196/63036 | 2025 | Philippine | Elepaño, 2025 | This mixed‑methods pilot study evaluates the deployment of an OpenMRS‑based system across urban, rural, and remote primary care settings in the Philippines (2016–2022), demonstrating consistently higher user acceptability and highlighting the platform’s importance for contextually tailored health IT in diverse LMIC settings | |
Implementation | Uwase, M., Ntakirutimana, I., Kayiranga, D., Mugisha, E., Twizere, C., Tumusiime, D., & Mugisha, M. (2025). Data quality assessment in mUzima‑OpenMRS: A mobile application used by community health workers for screening hypertension and diabetes in Rwanda. Studies in Health Technology and Informatics, 328, 387–391. https://doi.org/10.3233/SHTI250744 | 2025 | Rwanda | Uwase, 2025 | This study evaluates the completeness and uniqueness of data collected via the mUzima mobile app built on OpenMRS by community health workers in Rwanda, finding high-quality data (81% completeness, 89% uniqueness) while recommending stronger quality control features. | |
Digital Public Goods | Negussie, M. S., Gizaw, A. A., & Nielsen, P. (2025, May). On the generativity of digital public goods: DHIS2 and OpenMRS in Ethiopia. In M. Cunningham & P. Cunningham (Eds.), IST‑Africa 2025 Conference Proceedings (pp. x–x). IST‑Africa Institute & IIMC. | 2025 | Ethiopia | Negussie, 2025 | Analysis on OpenMRS, DHIS2 implementation in Ethiopia, using the concept of generativity to explore how global "Digital Public Goods" adapt to local contexts and what governance, architecture, and community mechanisms support successful adoption | |
Cervical Cancer | Sibomana, H., Ukwishaka, J., Mtenga, H., Luoga, O., Acosta, D., Fisher-Borne, M., ... & Hildebrand, M. R. (2025). Evaluating the Outcomes of Digital Health Solutions for Human Papilloma Virus Vaccination and Cervical Cancer Services in Rwanda: A Mixed-Method Study. Rwanda Medical Journal, 82(1), 48-59. | 2025 | Rwanda | Sibomana, 2025 | Study showing mUzima mobile app intergrated with OpenMRS used in over 28 district hospitals and two referral centres for cervical cancer services, which led to Rwanda’s screening coverage rise from 1% to 16% between 2018–2023 | |
ANC
Machine Learning | Sylvain, M. H., Nyabyenda, E. C., Uwase, M., Komezusenge, I., Ndikumana, F., & Ngaruye, I. (2025). Prediction of adverse pregnancy outcomes using machine learning techniques: evidence from analysis of electronic medical records data in Rwanda. BMC Medical Informatics and Decision Making, 25, 76. | 2025 | Rwanda | Sylvain, 2025 | https://bmcmedinformdecismak.biomedcentral.com/articles/10.1186/s12911-025-02921-z | Patient data here was captured in the Ministry’s OpenMRS based system across 25 hospitals to train Random Forest and Gradient Boosting models that predicted adverse pregnancy outcomes with up to 90.6 % accuracy (ROC‑AUC 0.85), highlighting OpenMRS as a critical source for data‑driven, high‑risk pregnancy identification |
Development
Machine Learning | Chowdhury, S. (2025). The Good, the Bad, and the Monstrous: Predicting Highly Change-Prone Source Code Methods at Their Inception. ACM Transactions on Software Engineering and Methodology. arXiv preprint arXiv:2408.05704. | 2025 | Global | Chowdhury, 2025 | A study introducing a machine learning approach to predict highly change-prone Java methods at their inception, in systems, OpenMRS being one of those studied, helping in identifying and managing volatile code components early in its platform development. …so as to enable proactive maintenance. | |
Implementation | Campbell, E., Bear Don’t Walk IV, O. J., Fraser, H., Gichoya, J., Wagholikar, K. B., Kanter, A. S., ... & Craig, S. (2025). Principles and implementation strategies for equitable and representative academic partnerships in global health informatics research. Journal of the American Medical Informatics Association, ocaf015. | 2025 | Global | Campbell, 2025 | https://academic.oup.com/jamia/advance-article/doi/10.1093/jamia/ocaf015/8011449 | A paper by Elizabeth Campbell, Andrew Kanter, among others, where they highlight some core principles for equitable, sustainable global health informatics collaborations… like a local development and leadership while engaging international collaborations for sustainability, scalability with limited funding, among other principles, very useful considerations in Implementations. |
Implementation
Evaluation | Pognon, P. R., Boima, F., & Mekonnen, Z. A. (2025). Health Workers’ Acceptance and Satisfaction on the Usability of the Digital Health Goods, in Kono District, Sierra Leone. Journal of Multidisciplinary Healthcare, 1067-1079. | 2025 | Sierra Leone | Pognon, 2025 | This survey of 151 health workers in PIH‑SL‑supported Sierra Leon clinics found that the OpenMRS was used to capture real‑time point‑of‑care patient data having a 72.2 % acceptance and satisfaction mainly due to the system’s perceived ease of use | |
HIV, KPs | Ensuring Equitable Access to Quality HIV Care for Key Populations in Complex Sociocultural Settings: Lessons from Nigeria Abdulsamad Salihu, Ibrahim Jahun, David Olusegun Oyedeji, Wole Fajemisin, Omokhudu Idogho, Samira Shehu, Jennifer Anyanti | 2025 | Nigeria | Salihu 2025 |
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Imlementation
Evaluation | Manyanye, S., Kapepo, M., Van Belle, J. P., & Mthwasi, G. (2025). Affordances and Constraints of the Open Medical Record System (OpenMRS) for Public Health Services Delivery in Lesotho. Procedia Computer Science, 256, 816-824. | 2025 | Lesotho | Manyanye, 2025 |
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Continuous Quality Improvement Implementation | Jean-Baptiste, M. C., Julmiste, T. M. V., & Ball, E. (2024). Health Information System Strengthening During Antenatal Care in Haiti: Continuous Quality Improvement Study. JMIR Formative Research, 8(1), e55000. | 2024 | Haiti | Jean-Baptiste, 2024 | https://s3.ca-central-1.amazonaws.com/assets.jmir.org/assets/preprints/preprint-55000-accepted.pdf | Based on a study in Haiti, where electronic documentation of prenatal visits in the OpenMRS increased from 15% to 89% over nine months. The findings highlight important implementation strategies to increase adoption & electronic visit documentation |
IoT Deep Neural Network Vital Signs Monitoring | Renold, A. P. (2024). PERS: Personalized environment recommendation system based on vital signs. Egyptian Informatics Journal, 28, 100580. | 2024 | Global | Renold, 2024 | https://www.sciencedirect.com/science/article/pii/S1110866524001439 | Findings on the potential of integrating PERS (Personalized Environment Recommendation System), an IoT driven system, with OpenMRS to continuously monitor patients’ vital signs and surrounding environmental conditions to provide personalized environmental adjustment recommendations |
Testing
LLMs | Chi, J., Wang, X., Huang, Y., Yu, L., Cui, D., Sun, J., & Sun, J. (2024). REACCEPT: Automated Co-evolution of Production and Test Code Based on Dynamic Validation and Large Language Models. arXiv preprint arXiv:2411.11033. | 2024 | Global | Chi, 2024 | Offers a way for systems like OpenMRS to automatically sync its test suite with evolving clinical features using REACCEPT, which leverages experience‑based prompt templates, retrieval‑ augmented generation, and dynamic validation with LLMs to fully automate production–test co‑evolution, achieving a 60.16 % accuracy on updating obsolete test cases | |
HIS Health Policy Evaluation | Bataliack, S., Ebongue, M., Karamagi, H., & Leon, J. (2024). Health data digitalization in Africa: unlocking the potential. COI: 20.500.12592/1icxw0z. | 2024 | Africa | Bataliack, 2024 |
| A comprehensive evaluation of digital health data systems in Africa and strategic recommendations for standardized, interoperable EMR adoption, OpenMRS being one of the main systems being evaluated with recommendations. |
Governance
Open Source
Sustainability | Yenişen Yavuz, E., Shrivastava, A., Riehle, D., & Putz, F. (2024, November). Governance Practices for Open Source Foundations in the Healthcare Sector. In International Conference on Software Business (pp. 382-397). Cham: Springer Nature Switzerland. | 2024 | Global | Yenişen, 2024 | https://link.springer.com/chapter/10.1007/978-3-031-85849-9_30 | A study on governance best practices across vendor‑led and user‑led open‑source healthcare foundations… with insights that OpenMRS can adopt to enhance its own community‑led governance, board structure, and member engagement processes. |
Decision- Support PWDs | Chichaeva, J. (2024). Global Digital Rehabilitation Summit 2024: Human-Centered Innovations and Beoyond. | 2024 | Cambodia | Chichaeva, 2024 | Highlights the impact of the use of OpenMRS within ICRC’s DCMS in enhancing rehabilitation service delivery and decision-making in low-resource settings, particularily to support PWDs | |
TB Tuberculosis | Sharifov, R., Nabirova, D., Tilloeva, Z. et al. TB treatment delays and associated risk factors in Dushanbe, Tajikistan, 2019–2021. BMC Infect Dis 24, 1398 (2024). | 2024 | Tajikistan | Sharifov 2024 |
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Data Interpretation | Nanyonga, S., Medina, P. B., Kozlakidis, Z., Garcia, D. L., Ivanova, D., & Katsaounis, P. (2024). Proliferation, ingestion, and interpretation of health data in low- and middle-income countries (LMICs). In Z. Kozlakidis, A. Muradyan, & K. Sargsyan (Eds.), Digitalization of medicine in low- and middle-income countries (Sustainable Development Goals Series). Springer. https://doi.org/10.1007/978-3-031-62332-5_25 | 2024 | Global | Nanyonga 2024 | https://link.springer.com/chapter/10.1007/978-3-031-62332-5_25 | This Book Chapter shows how digital health initiatives like OpenMRS are progressing from pilot stages to scalable, integrated healthcare solutions, emphasizing the importance of data proliferation, ingestion, and interpretation for sustainable impact. |
Process Optimization | Avagyan, A., Minasyan, E., Khachatryan, H., & Gevorgyan, S. (2024). Possible process optimization: Innovative digital health implementation models. In Z. Kozlakidis, A. Muradyan, & K. Sargsyan (Eds.), Digitalization of medicine in low- and middle-income countries (Sustainable Development Goals Series). Springer. https://doi.org/10.1007/978-3-031-62332-5_10 | 2024 | Global | Avagyan 2024 | https://link.springer.com/chapter/10.1007/978-3-031-62332-5_10 |
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Interoperability | Anantharaman, P., Shapiro, R., Varadharaju, V., & Locasto, M. E. (2024). A study of interoperability in electronic health record software. In Proceedings of the 2024 Workshop on Cybersecurity in Healthcare (HealthSec ’24) (pp. 8). ACM. https://doi.org/10.1145/3689942.3694743 | 2024 | Global | Anantharaman 2024 | FHIR Garden, a tool designed to compare FHIR implementations in EMRs including OpenMRS, identifying parser discrepancies and highlighting vulnerabilities that could impact patient data security. | |
COVID 19 Remote Health Monitoring
| Musheghyan, L., Harutyunyan, N., Sikder, A., Reid, M., Zhao, D., Lulejian, A., Dickhoner, J., Andonian, N., Aslanyan, L., Petrosyan, V., Sargsyan, Z., Shekherdimian, S., Dorian, A., & Espinoza, J. (2024). Managing patients with COVID-19 in Armenia using a remote monitoring system: Descriptive study. *JMIR Public Health and Surveillance, 10*, e57703. https://doi.org/10.2196/57703 | 2024 | Armenia | Musheghyan 2024 | This study highlights the effective use of an OpenMRS based system for a remote monitoring and home-based oxygen therapy program (COVID@home) in Armenia, showcasing its potential in resource-limited settings. | |
Implementation | Bouh, M. M., Hossain, F., Paul, P., et al. (2024). The impact of limited access to digital health records on doctors and their willingness to adopt electronic health record systems. Digital Health, 10. https://doi.org/10.1177/20552076241281626 | 2024 | Bangladesh | Bouh 2024 | The study investigates the challenges Bangladeshi doctors face due to limited access to digital health records, affecting their workload and clinical decision-making. It also highlights the impact and efficiency brought in by some OpenMRS-based implementations | |
Implementation | Uwambajimana, E., Rugirangoga, P., Musabyimana, E., et al. (2024, August 25). Assessment of the use of electronic medical records system and barriers in Rwanda (Version 1) Preprint. Research Square. https://doi.org/10.21203/rs.3.rs-4763866/v1 | 2024 | Rwanda | Uwambajimana 2024 |
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Implementation | Bakke, S. M. (2024). OpenMRS and Bahmni as an HIS in Ethiopia: Challenges with Integration and Interoperability with DHIS2 (Master's thesis). University of OSLO. | 2024 | Ethiopia | Bakke 2024 |
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Process optimization Implementation models | Avagyan, A., Minasyan, E., Khachatryan, H., Gevorgyan, S. (2024). Possible Process Optimization: Innovative Digital Health Implementation Models. In: Kozlakidis, Z., Muradyan, A., Sargsyan, K. (eds) Digitalization of Medicine in Low- and Middle-Income Countries. Sustainable Development Goals Series. Springer, Cham. https://doi.org/10.1007/978-3-031-62332-5_10 | 2024 | Global | Avagyan 2024 | https://link.springer.com/chapter/10.1007/978-3-031-62332-5_10 |
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Diabetes Hypertension User Experience | Ntakirutimana, I., Kayiranga, D., Muhirwa, A., Nkurunziza, E., Sibomana, E., Uwamahoro, A., Igihozo, T., Ndoli, A., Niyonshuti, E., Rwubaka, E., Tuyishime, I., Umutoniwase, E. M., & Mugisha, M. (2024). Nurses' Experience of Using an Electronic Medical Records - OpenMRS Module for the Management of Hypertension and Diabetes in Rwanda: A Qualitative Study. Studies in health technology and informatics, 316, 1048–1052. https://doi.org/10.3233/SHTI240590 | 2024 | Rwanda | Ntakirutimana 2024 | Study found the OpenMRS system useful in simplifying patient care and reporting as nurses also could use the system with limited and manageable challenges. . Some barriers related to the use of the system were slowness of the system, turnover of trained users, and some challenges related to system design and navigations. | |
Water Quality Epidemiology
Rural | Finkelstein, A. L. (2024). Is Our Water Safe to Drink? A View from Rural Honduras (Publication No. 46199) [Master Essay, University of Pittsburgh]. | 2024 | Rural Honduras | Finkelstein 2024 | Implementation of OpenMRS in San Jose del Negrito, Honduras, for improved disease surveillance and healthcare management. The system is intented to track child growth, prenatal care, and malnutrition and also how they tie to the public water quality. | |
Implementation
HIV Interoperability
| Maoeng, M., Bruce, K., Motebang, M., Chen, C. W., Lecher, S., Gadisa, T., Saito, S., & Ntsaba, M. (2024). From Disease Specific to Universal Health Coverage in Lesotho: Successes and Challenges Encountered in Lesotho’s Digital Health Journey. Oxford Open Digital Health. DOI:10.1093/oodh/oqae021 | 2024 | Lesotho | Maoeng 2024 | Highlights opportunities & challenges of scaling/expanding from a system ( Based on OpenMRS Bahmni Distro) that was built to serve only HIV & TB needs, to multiple areas to become functional across all reportable diseases. Shows need for Core elements of digital health systems including governance, security, power, & connectivity to be in place. | |
Implementation Quality Improvement HIV | Fraser H, Mugisha M, Bacher I, Ngenzi J, Seebregts C, Umubyeyi A, Condo J. (2024) | 2024 | Rwanda | Fraser 2024 | Study on 50 health facilities (HFs) using OpenMRS, an EHR system that supports HIV care in Rwanda, and performed a data quality evaluation | |
Implementation Improvement
| D. RWEGASIRA et al. (2024), "Deployment and Innovation Processes of Integrated Electronic Medical Record (EMR) System: A Case of University Health Centre Living Lab in Tanzania," 2024 IST-Africa Conference (IST-Africa), Dublin, Ireland, 2024, pp. 1-8, doi: 10.23919/IST-Africa63983.2024.10569206. | 2024 | Tanzania | Rwegasira 2024 | Challenges identified and development approaches, results, and system implementation benefits, for iCareConnect+, an OpenMRS implementation at University of Dar es Salaam Health Centre living lab. | |
Maternal Healthcare | M. CHEMISTO et al.(2024). "ICT for Improved Maternal Healthcare in Uganda: A Systematic Literature Review," 2024 IST-Africa Conference (IST-Africa), Dublin, Ireland, 2024, pp. 1-11, doi: 10.23919/IST-Africa63983.2024.10569857. | 2024 | Uganda | CHEMISTO 2024 | The influence of ICTs on Uganda's maternal health sector development based on the premise that ICTs like OpenMRS, have supported improvements in maternal health services such as antenatal, pregnancy, and postnatal care. | |
HIV HIV viral suppression HIV medication Implementation
| Hedima, E. W., Ohieku, J. D., David, E. A., Ikunaiye, N. Y., Nasir, A., Alfa, M. A., Abubakar S., Bwiyam, I. K., & Bitrus, T. Z. (2024). | 2024 | Nigeria | Hedima 2024 | https://www.sciencedirect.com/science/article/pii/S2667276624000702 | Study conducted with data collected using Nigeria-OpenMRS revealed that majority of the patients achieved viral suppression with moderate degree of medication-related burden. Proposed Targeted interventions toward younger patients, females and patients with unsuppressed viral loads |
Antenatal Care Quality improvement Implementation | Casella Jean-Baptiste M, Vital Julmiste T, Ball E (2024). Health Information System Strengthening During Antenatal Care in Haiti: Continuous Quality Improvement Study | 2024 | Haiti | Jean-Baptiste 2024 | Improved data use and quality for antenatal patient care using OpenMRS at Hôpital Universitaire de Mirebalais (Haiti). Zanmi Lasante and Partners In Health | |
Interoperability Standards-based HL7 FHIR | Bacher I, Goodrich M, Kimaina A, Seaton M, Faulkenberry G, Vaish S, Flowers J, Fraser HS. FHIRing up OpenMRS: Architecture, Implementation and Real-World Use-Cases in Global Health. AMIA Jt Summits Transl Sci Proc. 2024 May 31;2024:162-171. PMID: 38827065; PMCID: PMC11141833. |